{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T17:53:03Z","timestamp":1759341183333},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Granuloma annulare (GA) is a noninfectious necrobiotic granuloma, which can present as localized or generalized patterns. We present a case of generalized GA with multiple large open comedones over the lesions in a woman with hypothyroidism and diabetes mellitus. GA is associated with collagen and elastic-fibre damage, which may lead to loss of follicular support and resultant open comedone formation, analogous to solar elastosis or senile comedones. The rapid recovery of our patient after treatment with of oral hypoglycaemics supports the role of insulin resistance as a predisposing factor for GA.<\/jats:p>","DOI":"10.1111\/j.1365-2230.2011.04025.x","type":"journal-article","created":{"date-parts":[[2011,3,11]],"date-time":"2011-03-11T10:06:02Z","timestamp":1299837962000},"page":"495-498","source":"Crossref","is-referenced-by-count":8,"title":["Generalized granuloma annulare with open comedones in photoexposed areas"],"prefix":"10.1093","volume":"36","author":[{"given":"P.","family":"Bhushan","sequence":"first","affiliation":[{"name":"Skin Institute and School of Dermatology, Greater Kailash, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Skin Institute and School of Dermatology, Greater Kailash, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Yadav","sequence":"additional","affiliation":[{"name":"Skin Institute and School of Dermatology, Greater Kailash, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Baliyan","sequence":"additional","affiliation":[{"name":"Skin Institute and School of Dermatology, Greater Kailash, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,7,1]]},"reference":[{"key":"2023012703541175900_b1","first-page":"1421","volume-title":"Dermatology","author":"Howard","year":"2009"},{"key":"2023012703541175900_b2","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1600-0781.2006.00230.x","article-title":"Open comedones overlying granuloma annulare in a photoexposed area","volume":"22","author":"Sudy","year":"2006","journal-title":"Photodermatol Photoimmunol Photomed"},{"key":"2023012703541175900_b3","first-page":"647","article-title":"Papular elastolytic giant cell granuloma: a clinical variant of annular elastolytic giant cell granuloma or generalized granuloma annulare?","volume":"9","author":"Morita","year":"1999","journal-title":"Eur J Dermatol"},{"key":"2023012703541175900_b4","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4103\/0378-6323.51259","article-title":"Granuloma multiforme. A report from India","volume":"75","author":"Kumari","year":"2009","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"2023012703541175900_b5","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1111\/j.1600-0560.2008.01169.x","article-title":"Collagen-elastic tissue changes and vascular involvement in granuloma annulare: a review of 35 cases","volume":"36","author":"G\u00fcne\u015f","year":"2009","journal-title":"J Cutan Pathol"},{"key":"2023012703541175900_b6","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0190-9622(89)70004-9","article-title":"Generalized granuloma annulare: histopathology and immunopathology. Systematic review of 100 cases and comparison with localized granuloma annulare","volume":"20","author":"Dabski","year":"1989","journal-title":"J Am Acad Dermatol"},{"key":"2023012703541175900_b7","doi-asserted-by":"crossref","first-page":"113","DOI":"10.5021\/ad.2009.21.2.113","article-title":"Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea","volume":"21","author":"Yun","year":"2009","journal-title":"Ann Dermatol"},{"key":"2023012703541175900_b8","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1067\/mjd.2003.104","article-title":"Localized granuloma annulare and autoimmune thyroiditis in adult women: a case-control study","volume":"48","author":"V\u00e1zquez-L\u00f3pez","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"2023012703541175900_b9","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1111\/j.1365-2230.2008.03183.x","article-title":"Generalized granuloma annulare in a photosensitive distribution resolving with scarring and milia formation","volume":"34","author":"Gass","year":"2009","journal-title":"Clin Exp Dermatol"},{"key":"2023012703541175900_b10","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1525-1470.2010.01099.x","article-title":"Links between granuloma annulare, necrobiosis lipoidica diabeticorum and childhood diabetes: a matter of time?","volume":"27","author":"Davison","year":"2010","journal-title":"Pediatr Dermatol"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2230.2011.04025.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/36\/5\/495\/46913277\/ced0495.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/36\/5\/495\/46913277\/ced0495.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T04:11:21Z","timestamp":1674792681000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/36\/5\/495\/6622447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,1]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2011,7,1]]},"published-print":{"date-parts":[[2011,7,1]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2230.2011.04025.x","relation":{},"ISSN":["1365-2230","0307-6938"],"issn-type":[{"value":"1365-2230","type":"electronic"},{"value":"0307-6938","type":"print"}],"subject":[],"published-other":{"date-parts":[[2011,7,1]]},"published":{"date-parts":[[2011,7,1]]}}}