{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T16:49:14Z","timestamp":1791132554717,"version":"4.1.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,12,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Blastocystis hominis is a common intestinal parasite, with a prevalence in developing countries of up to 50%. The aim of this study was to investigate the association of this parasite with urticaria by determining the genotypic isotypes in the Egyptian population. In total, 54 patients with urticaria and 50 controls were enrolled in the study. Stool samples were examined and assessed by PCR. The parasite was detected in a significantly higher number (P &amp;lt; 0.001) of the patient group than the control group. There was no significant difference between the patients with acute and those with chronic urticaria (P = 0.2). The amoeboid form was found in 60.6% of Blastocystis-positive patients with urticaria, but in none of the healthy controls. Subtype 3 was the only isolate found in both the patient and control groups. We recommend treatment for Blastocystis-positive patients with urticaria in developing countries. The prevalence is much lower (around 10%) in developed countries, where treatment should only be considered in the absence of other possible causes of urticaria.<\/jats:p>","DOI":"10.1111\/j.1365-2230.2011.04127.x","type":"journal-article","created":{"date-parts":[[2011,7,26]],"date-time":"2011-07-26T13:51:43Z","timestamp":1311688303000},"page":"908-910","source":"Crossref","is-referenced-by-count":36,"title":["Study of <i>Blastocystis hominis<\/i> isolates in urticaria: a case\u2013control study"],"prefix":"10.1093","volume":"36","author":[{"given":"N. M.","family":"Zuel-Fakkar","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Faculty of Medicine, Ain Shams University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. M.","family":"Abdel Hameed","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. M.","family":"Hassanin","sequence":"additional","affiliation":[{"name":"Clinical Pathology, Molecular Department of Medical Research Center, Faculty of Medicine, Ain Shams University, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,12,1]]},"reference":[{"key":"2023012703541727400_b1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00005-008-0013-6","article-title":"Current advances in the management of urticaria","volume":"56","author":"Khalaf","year":"2008","journal-title":"Arch Immunol Therp Exp"},{"key":"2023012703541727400_b2","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.parint.2010.03.009","article-title":"Blastocystis sp. subtype2 detection during recurrence of gastrointestinal and urticarial symptoms","volume":"59","author":"Vogelberg","year":"2010","journal-title":"Parasitol Int"},{"key":"2023012703541727400_b3","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2340\/00015555-0338","article-title":"Acute urticaria associated with amoeboid forms of Blastocystis sp. subtype 3","volume":"88","author":"Katsarou-Katsari","year":"2008","journal-title":"Acta Derm Venereol"},{"key":"2023012703541727400_b4","first-page":"28","article-title":"Is Blastocystis hominis an opportunist agent","volume":"31","author":"Al","year":"2007","journal-title":"Turkiye Parazitol Derg"},{"key":"2023012703541727400_b5","first-page":"599","article-title":"Prevalence and clinical features of Dientamoeba fragilis infections in patients suspected to have intestinal parasitic infection","volume":"37","author":"Rayan","year":"2007","journal-title":"J Egypt Soc Parasitol"},{"key":"2023012703541727400_b6","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s00436-006-0186-z","article-title":"Genetic variability of Blastocystis hominis isolates in china","volume":"99","author":"Yan","year":"2006","journal-title":"Parasitol Res"},{"key":"2023012703541727400_b7","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1080\/00015550410025949","article-title":"Cutaneous lesions in Blastocystis hominis infection","volume":"84","author":"Valsecchi","year":"2004","journal-title":"Acta Derm Venereol"},{"key":"2023012703541727400_b8","first-page":"117","article-title":"Chronic urticaria and Blastocystis hominis infection: a case report","volume":"8","author":"Pasqui","year":"2004","journal-title":"Eur Rev Med Pharmacol"},{"key":"2023012703541727400_b9","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1017\/S0031182009991351","article-title":"High levels of oxidative stress in rats infected with Blastocystis hominis","volume":"137","author":"Chandramathi","year":"2010","journal-title":"Parasitology"},{"key":"2023012703541727400_b10","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1046\/j.1365-2230.2003.01264.x","article-title":"Over-expression of Mn-superoxide dismutase as a marker of oxidative stress in lesional skin of chronic idiopathic urticaria","volume":"28","author":"Raho","year":"2003","journal-title":"Clin Exp Dermatol"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2230.2011.04127.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/36\/8\/908\/46914800\/ced0908.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/36\/8\/908\/46914800\/ced0908.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T04:12:33Z","timestamp":1674792753000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/36\/8\/908\/6622417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,1]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2011,12,1]]},"published-print":{"date-parts":[[2011,12,1]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2230.2011.04127.x","relation":{},"ISSN":["1365-2230","0307-6938"],"issn-type":[{"value":"1365-2230","type":"electronic"},{"value":"0307-6938","type":"print"}],"subject":[],"published-other":{"date-parts":[[2011,12,1]]},"published":{"date-parts":[[2011,12,1]]}}}