{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T19:38:49Z","timestamp":1700768329096},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,3,17]],"date-time":"2008-03-17T00:00:00Z","timestamp":1205712000000},"content-version":"vor","delay-in-days":9937,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[1981,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>We have measured basal thyrotropin (TSH) in 945 consecutive patients of a general medical department. Additional thyroid tests were carried out in patients with elevated TSH. Thirty patients (3\u00b71%) had subclinical hypothyroidism, i.e. an elevated TSH with no clinical signs and with a normal free thyroxine index. A cause was found in only fifteen of these thirty patients. Thirteen additional patients (1\u00b737%) had mild or overt primary hypothyroidism, three of which were already diagnosed. This prevalence is three times higher than that found in a retrospective survey at the same hospital. Of the ten newly\u2010detected cases five were discharged on thyroid hormone replacement. In two patients the antithyroid drugs which were the cause of hypothyroidism were discontinued. The remaining three patients had severe non\u2010thyroidal illnesses and thyroid hormone was not prescribed. A cause for the hypothyroidism (autoimmune thyroid disease, post\u2010radioiodine, post\u2010thyroidectomy or antithyroid drugs) was established in all but two cases. The data suggest that thyroid function tests (preferably a TSH) should be performed on any patient with prior treatment to the thyroid and, in addition with very broad indications, perhaps even routinely, in all women over 50 years of age.<\/jats:p>","DOI":"10.1111\/j.1365-2265.1981.tb00366.x","type":"journal-article","created":{"date-parts":[[2008,3,17]],"date-time":"2008-03-17T13:09:41Z","timestamp":1205759381000},"page":"69-74","source":"Crossref","is-referenced-by-count":23,"title":["PREVALENCE OF VARIOUS DEGREES OF HYPOTHYROIDISM AMONG PATIENTS OF A GENERAL MEDICAL DEPARTMENT"],"prefix":"10.1111","volume":"14","author":[{"given":"M.","family":"RINIKER","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"TI\u00c8CHE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. A.","family":"LUPI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"GROB","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"STUDER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"B\u00dcRGI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,3,17]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"1119","article-title":"Diagnostische Bedeutung der Schilddr\u00fcsenantik\u00f6rper.","volume":"107","author":"Akert F.G.","year":"1977","journal-title":"Schweizerische Medizinische Wochenschrift"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5971.601"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)90177-5"},{"key":"e_1_2_1_5_1","first-page":"255","article-title":"Statistical methods applied to the diagnosis of thyroid disease.","volume":"38","author":"Billewicz W.Z.","year":"1969","journal-title":"Quarterly Journal of Medicine"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5854.657"},{"key":"e_1_2_1_7_1","first-page":"1152","article-title":"Bedeutung der Schilddr\u00fcsenkrankheiten in einer allgemeininternistischen Klinik.","volume":"108","author":"Geiser J.","year":"1978","journal-title":"Schweizerische Medizinische Wochenschrift"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6004.257"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1001\/jama.1979.03300030019013","article-title":"The aging thyroid\u2014increased prevalence of elevated serum thyrotropin levels in the elderly.","volume":"242","author":"Sawin C.T.","year":"1979","journal-title":"Journal of the American Medical Association"},{"key":"e_1_2_1_10_1","first-page":"1839","article-title":"Entwicklung eines einfachen oralen Kurztests mil dem TSH\u2010releasing\u2010hormon (TRH) und dessen Anwendung in der Schilddr\u00fcsendiagnostik.","volume":"106","author":"Staub J.J.","year":"1976","journal-title":"Schweizerische Medizinische Wochenschrift"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1977.tb01340.x"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(67)92235-0"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6067.993"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2265.1981.tb00366.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2265.1981.tb00366.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T11:38:59Z","timestamp":1699702739000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2265.1981.tb00366.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1981,1]]}},"alternative-id":["10.1111\/j.1365-2265.1981.tb00366.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2265.1981.tb00366.x","archive":["Portico"],"relation":{},"ISSN":["0300-0664","1365-2265"],"issn-type":[{"value":"0300-0664","type":"print"},{"value":"1365-2265","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,1]]}}}