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Tissue concentrations of adiponectin, ICAM\u20101, TNF\u2010\u03b1 and H\u2010FABP in the atherosclerotic plaques were measured.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Blood glucose and tissue levels of TNF\u2010\u03b1 and ICAM\u20101 were negatively correlated with tissue levels of adiponectin, whereas TNF\u2010\u03b1 was positively correlated with ICAM\u20101 in atherosclerotic plaques. In addition, there was a positive correlation between blood glucose and tissue levels of both TNF\u2010\u03b1 and ICAM\u20101. TNF\u2010\u03b1 and ICAM\u20101 levels in atherosclerotic plaques appear to progressively increase whereas adiponectin levels progressively decrease with smoking status. Atherosclerotic tissue levels of these substances are also altered in diabetes.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> The data are in accord with those in prior publications on the detection and quantification of various inflammatory cytokines in atherosclerotic plaques. 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