{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T12:52:31Z","timestamp":1781009551471,"version":"3.54.1"},"reference-count":56,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1392,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1111\/j.1365-2265.2011.04148.x","type":"journal-article","created":{"date-parts":[[2011,6,23]],"date-time":"2011-06-23T12:56:09Z","timestamp":1308833769000},"page":"725-729","source":"Crossref","is-referenced-by-count":39,"title":["Mineralocorticoid antagonism: a novel way to treat sarcopenia and physical impairment in older people?"],"prefix":"10.1111","volume":"75","author":[{"given":"Louise A.","family":"Burton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion E. T.","family":"McMurdo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan D.","family":"Struthers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,11,9]]},"reference":[{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1152\/jappl.1979.46.3.451","article-title":"Muscle strength and speed of movement in relation to age and muscle morphology","volume":"46","author":"Larsson","year":"1979","journal-title":"Journal of Applied Physiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF02982703","article-title":"The developmental origins of sarcopenia","volume":"12","author":"Sayer","year":"2008","journal-title":"The Journal of Nutrition, Health and Aging"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.3945\/ajcn.2009.28256","article-title":"Rapid loss of appendicular skeletal muscle mass is associated with higher all-cause mortality in older men: the prospective MINOS study","volume":"91","author":"Szulc","year":"2010","journal-title":"American Journal of Clinical Nutrition"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000093656","article-title":"Sarcopenia - a potential target for angiotensin-converting enzyme inhibition?","volume":"52","author":"Sumukadas","year":"2006","journal-title":"Gerontology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1503\/cmaj.061339","article-title":"Effect of perindopril on physical function in elderly people with functional impairment: a randomized controlled trial","volume":"177","author":"Sumukadas","year":"2007","journal-title":"Canadian Medical Association Journal"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1152\/jappl.1993.75.5.2125","article-title":"Muscle metabolism during exercise in young and older untrained and endurance-trained men","volume":"75","author":"Coggan","year":"1993","journal-title":"Journal of Applied Physiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB7|cit7","first-page":"11","article-title":"Human aging, muscle mass, and fiber-type composition","volume":"50","author":"Lexell","year":"1995","journal-title":"The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1503\/cmaj.051351","article-title":"Health benefits of physical activity: the evidence","volume":"174","author":"Warburton","year":"2006","journal-title":"Canadian Medical Association Journal"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1152\/jn.1999.82.5.2081","article-title":"Effects of aging on motor-unit control properties","volume":"82","author":"Erim","year":"1999","journal-title":"Journal of Neurophysiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000026373","article-title":"The thymus-pituitary axis and its changes during aging","volume":"6","author":"Goya","year":"1999","journal-title":"Neuroimmunomodulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1152\/japplphysiol.91551.2008","article-title":"Aging, exercise, and muscle protein metabolism","volume":"106","author":"Koopman","year":"2009","journal-title":"Journal of Applied Physiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"C1032","DOI":"10.1152\/ajpcell.1996.271.4.C1032","article-title":"Effects of aging on sarcoplasmic reticulum function and contraction duration in skeletal muscles of the rat","volume":"40","author":"Narayanan","year":"1996","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1113\/jphysiol.1992.sp019160","article-title":"Calcium current activation and charge movement in denervated mammalian skeletal-muscle fibers","volume":"451","author":"Delbono","year":"1992","journal-title":"The Journal of Physiology-London"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1469-7793.2000.t01-1-00203.x","article-title":"Oxidative capacity and ageing in human muscle","volume":"526","author":"Conley","year":"2000","journal-title":"The Journal of Physiology-London"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.mce.2003.10.054","article-title":"Aldosterone, mineralocorticoid receptors and vascular inflammation","volume":"217","author":"Funder","year":"2004","journal-title":"Molecular and Cellular Endocrinology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"4883","DOI":"10.1074\/jbc.273.9.4883","article-title":"Myocardial production of aldosterone and corticosterone in the rat - physiological regulation","volume":"273","author":"Silvestre","year":"1998","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1210\/en.141.10.3871","article-title":"Aldosterone: a mediator of myocardial necrosis and renal arteriopathy","volume":"141","author":"Rocha","year":"2000","journal-title":"Endocrinology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1161\/01.CIR.82.5.1730","article-title":"Hormones regulating cardiovascular function in patients with severe congestive-heart-failure and their relation to mortality","volume":"82","author":"Swedberg","year":"1990","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1136\/hrt.2003.017368","article-title":"Effects of spironolactone on endothelial function, vascular angiotensin converting enzyme activity, and other prognostic markers in patients with mild heart failure already taking optimal treatment","volume":"90","author":"Macdonald","year":"2004","journal-title":"Heart"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.yjmcc.2005.04.001","article-title":"Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo","volume":"39","author":"Burniston","year":"2005","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1161\/01.CIR.100.10.1056","article-title":"Comparison of candesartan, enalapril, and their combination in congestive heart failure - Randomized evaluation of strategies for left ventricular dysfunction (RESOLVD) pilot study - The RESOLVD pilot study investigators","volume":"100","author":"McKelvie","year":"1999","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1136\/heart.88.4.373","article-title":"Perindopril improves six minute walking distance in older patients with left ventricular systolic dysfunction: a randomised double blind placebo controlled trial","volume":"88","author":"Hutcheon","year":"2002","journal-title":"Heart"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0002-9149(01)02261-5","article-title":"Relation of aldosterone \u201cescape\u201d despite angiotensin-converting enzyme inhibitor administration to impaired exercise capacity in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy","volume":"89","author":"Cicoira","year":"2002","journal-title":"American Journal of Cardiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB24|cit24","first-page":"28","article-title":"Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in chronic heart failure patients","volume":"23","author":"Cicoira","year":"2002","journal-title":"European Heart Journal"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1139\/h05-141","article-title":"Blood flow to exercising limbs varies with age, gender, and training status","volume":"30","author":"Koch","year":"2005","journal-title":"Canadian Journal of Applied Physiology-Revue Canadienne de Physiologie Appliquee"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1007\/s000180050359","article-title":"Effects of nitric oxide on the contraction of skeletal muscle","volume":"55","author":"Marechal","year":"1999","journal-title":"Cellular and Molecular Life Sciences"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/jemt.1165","article-title":"NO message from muscle","volume":"55","author":"Grozdanovic","year":"2001","journal-title":"Microscopy Research and Technique"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1161\/01.CIR.0000015854.60710.10","article-title":"Mineralocorticoid receptor antagonism in experimental atherosclerosis","volume":"105","author":"Rajagopalan","year":"2002","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nm1545","article-title":"Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity","volume":"13","author":"Leopold","year":"2007","journal-title":"Nature Medicine"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0735-1097(01)01729-6","article-title":"Addition of spironolactone to angiotensin-converting enzyme inhibition in heart failure improves endothelial vasomotor dysfunction - role of vascular superoxide anion formation and endothelial nitric oxide synthase expression","volume":"39","author":"Bauersachs","year":"2002","journal-title":"Journal of the American College of Cardiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1161\/01.CIR.101.6.594","article-title":"Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I\/angiotensin II conversion in patients with chronic heart failure","volume":"101","author":"Farquharson","year":"2000","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF00637611","article-title":"Effect of spironolactone on systemic blood-pressure, limb blood-flow and response to sympathetic-stimulation in hypertensive patients","volume":"21","author":"Clement","year":"1982","journal-title":"European Journal of Clinical Pharmacology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1007\/s00125-008-0972-5","article-title":"Spironolactone for poorly controlled hypertension in type 2 diabetes: conflicting effects on blood pressure, endothelial function, glycaemic control and hormonal profiles","volume":"51","author":"Swaminathan","year":"2008","journal-title":"Diabetologia"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1046\/j.1365-2249.2003.02249.x","article-title":"Spironolactone inhibits production of proinflammatory cytokines, including tumour necrosis factor-alpha and interferon-gamma, and has potential in the treatment of arthritis","volume":"134","author":"Bendtzen","year":"2003","journal-title":"Clinical and Experimental Immunology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jnutbio.2005.11.002","article-title":"Tumor necrosis factor alpha signaling in skeletal muscle: effects of age and caloric restriction","volume":"17","author":"Dirks","year":"2006","journal-title":"The Journal of Nutritional Biochemistry"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB36|cit36","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1056\/NEJM199610173351603","article-title":"Apoptosis in myocytes in end-stage heart failure","volume":"335","author":"Narula","year":"1996","journal-title":"New England Journal of Medicine"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0735-1097(98)00626-3","article-title":"Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance","volume":"33","author":"Adams","year":"1999","journal-title":"Journal of the American College of Cardiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB38|cit38","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1161\/01.CIR.96.2.526","article-title":"Hormonal changes and catabolic\/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia","volume":"96","author":"Anker","year":"1997","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB39|cit39","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1007\/s10495-008-0216-7","article-title":"Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice","volume":"13","author":"Braga","year":"2008","journal-title":"Apoptosis"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB40|cit40","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/0002-8703(79)90108-X","article-title":"Ventricular extra-systoles and intracellular electrolytes before and after potassium and magnesium infusions in patients on diuretic treatment","volume":"97","author":"Dyckner","year":"1979","journal-title":"American Heart Journal"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB41|cit41","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1111\/j.1530-0277.1992.tb01906.x","article-title":"Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics","volume":"16","author":"Gullestad","year":"1992","journal-title":"Alcoholism, Clinical and Experimental Research"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB42|cit42","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1046\/j.1365-2796.2002.01008.x","article-title":"Muscle strength, Na, K-pumps, magnesium and potassium in patients with alcoholic liver cirrhosis - relation to spironolactone","volume":"252","author":"Aagaard","year":"2002","journal-title":"Journal of Internal Medicine"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB43|cit43","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1046\/j.1365-2796.2003.01100.x","article-title":"Decreased muscle strength and contents of Mg and Na, K-pumps in chronic alcoholics occur independently of liver cirrhosis","volume":"253","author":"Aagaard","year":"2003","journal-title":"Journal of Internal Medicine"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB44|cit44","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1152\/physrev.00011.2003","article-title":"Na+-K+ pump regulation and skeletal muscle contractility","volume":"83","author":"Clausen","year":"2003","journal-title":"Physiological Reviews"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB45|cit45","doi-asserted-by":"crossref","first-page":"E110","DOI":"10.1152\/ajpendo.00258.2007","article-title":"Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat","volume":"295","author":"Lastra","year":"2008","journal-title":"American Journal of Physiology. Endocrinology and Metabolism"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB46|cit46","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1161\/01.CIR.98.17.1742","article-title":"Improved exercise tolerance after losartan and enalapril in heart failure - Correlation with changes in skeletal muscle myosin heavy chain composition","volume":"98","author":"Vescovo","year":"1998","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB47|cit47","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/(SICI)1097-0185(199610)246:2<208::AID-AR7>3.0.CO;2-X","article-title":"Capillary and muscle fiber type changes in DOCA-salt hypertensive rats","volume":"246","author":"Hernandez","year":"1996","journal-title":"The Anatomical Record"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB48|cit48","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1016\/S0735-1097(01)01237-2","article-title":"Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype","volume":"37","author":"Cicoira","year":"2001","journal-title":"Journal of the American College of Cardiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB49|cit49","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1136\/bmj.318.7180.368","article-title":"Prevalence and clinical characteristics of left ventricular dysfunction among elderly patients in general practice setting: cross sectional survey","volume":"318","author":"Morgan","year":"1999","journal-title":"British Medical Journal"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB50|cit50","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1751-7133.2009.00056.x","article-title":"Effect of aldosterone antagonism on exercise tolerance, Doppler diastolic function, and quality of life in older women with diastolic heart failure","volume":"15","author":"Daniel","year":"2009","journal-title":"Congestive Heart Failure"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB51|cit51","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1161\/01.CIR.83.6.1849","article-title":"Pathological hypertrophy and cardiac interstitium - fibrosis and renin-angiotensin-aldosterone system","volume":"83","author":"Weber","year":"1991","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB52|cit52","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1006\/jmcc.2002.2115","article-title":"Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat","volume":"34","author":"De Angelis","year":"2002","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB53|cit53","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/BF00542411","article-title":"Effects of spironolactone on serum and muscle electrolytes in patients on long-term diuretic therapy for congestive-heart-failure and or arterial-hypertension","volume":"30","author":"Dyckner","year":"1986","journal-title":"European Journal of Clinical Pharmacology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB54|cit54","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1159\/000168356","article-title":"Aldosterone in congestive-heart-failure - analysis of determinants and role in sodium retention","volume":"11","author":"Hensen","year":"1991","journal-title":"American Journal of Nephrology"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB55|cit55","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1161\/01.CIR.103.1.72","article-title":"Aldosterone production is activated in failing ventricle in humans","volume":"103","author":"Mizuno","year":"2001","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2265.2011.04148.x-BIB56|cit56","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure","volume":"341","author":"Pitt","year":"1999","journal-title":"New England Journal of Medicine"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2265.2011.04148.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2265.2011.04148.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T08:18:31Z","timestamp":1613204311000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.1111\/j.1365-2265.2011.04148.x"}},"subtitle":["<i>Mineralocorticoid antagonism<\/i>"],"short-title":[],"issued":{"date-parts":[[2011,11,9]]},"references-count":56,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,12]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2265.2011.04148.x","relation":{},"ISSN":["0300-0664"],"issn-type":[{"value":"0300-0664","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11,9]]}}}