{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T02:08:16Z","timestamp":1793066896520,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,4,5]],"date-time":"2012-04-05T00:00:00Z","timestamp":1333584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Aim and Background\u2002<\/jats:bold>\n                    Hashimoto\u2019s thyroiditis (HT) is a common autoimmune thyroid disease with a female preponderance. Renal involvement in HT is not uncommon. In the present study, we aimed to define the frequency and characteristics of the glomerular diseases associated with HT and further the understanding of any common pathogenesis between HT and glomerular disease.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Materials and Methods\u2002<\/jats:bold>\n                    We reviewed retrospectively 28 patients with HT who were referred to our Department because of unexplained haematuria, proteinuria or renal impairment from 2007 to 2011. Routine laboratory investigations including blood count, serum biochemistry, urinalysis and 24\u2010h urinary protein excretion were performed on all patients. Renal biopsy was performed in 20 patients with HT, and the specimens were examined by light microscopy and immunofluorescence staining.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results\u2002<\/jats:bold>\n                    We detected four cases of focal segmental glomerulosclerosis (FSGS), four membranous glomerulonephritis (MGN), two minimal\u2010change disease (MCD), three immunoglobulin A nephritis (IgAN), three chronic glomerulonephritis (CGN) and one amyloidosis. In three patients, the renal biopsy findings were nonspecific. Daily urinary protein excretion and glomerular filtration rates were found to be independent of the level of thyroid hormone and thyroid\u2010specific autoantibodies.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion\u2002<\/jats:bold>\n                    Glomerular pathologies associated with HT are similar to those in the general population, the most common lesions being MGN, FSGS and IgA nephritis.\n                  <\/jats:p>","DOI":"10.1111\/j.1365-2265.2011.04302.x","type":"journal-article","created":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T07:57:53Z","timestamp":1321948673000},"page":"759-762","source":"Crossref","is-referenced-by-count":16,"title":["Coexistent findings of renal glomerular disease with Hashimoto\u2019s thyroiditis"],"prefix":"10.1111","volume":"76","author":[{"given":"G\u00fclay","family":"Ko\u00e7ak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fclent","family":"Huddam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alper","family":"Azak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Ortabozkoyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Duranay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70189-4"},{"key":"e_1_2_6_3_2","first-page":"675","article-title":"Autoimmune thyroid diseases in children","volume":"2011","author":"Cappa M.","year":"2010","journal-title":"Journal of Thyroid Research"},{"issue":"3","key":"e_1_2_6_4_2","first-page":"43","article-title":"[Membranoproliferative glomerulonephritis associated with autoimmune thyroiditis]","volume":"24","author":"Valent\u00edn M.","year":"2004","journal-title":"Nefrologia"},{"key":"e_1_2_6_5_2","first-page":"595","article-title":"[Membranous glomerulonephritis secondary to Hashimoto\u2019s thyroiditis]","volume":"30","author":"Ruiz\u2010Zorrilla L\u00f3pez C.","year":"2010","journal-title":"Nefrologia"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/105072502760339370"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)56400-0"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e3182173341"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200721100-00002"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/10507250150500676"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2005.18.3.319"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-1009-5"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.62.8.811"},{"key":"e_1_2_6_14_2","first-page":"605","article-title":"The changes of urine protein and serum beta 2\u2010microglobulin in autoimmune thyroid disease","volume":"33","author":"Gao Y.M.","year":"1994","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365591003636604"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2008.12.008"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr401"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn554"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10165-010-0345-z"},{"key":"e_1_2_6_20_2","first-page":"406","article-title":"IgA nephropathy and autoimmune thyroiditis","volume":"57","author":"Enr\u00edquez R.","year":"2002","journal-title":"Clinical Nephrology"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e31815b9d51"},{"key":"e_1_2_6_22_2","first-page":"233","article-title":"Generalized amyloidosis associated with Hashimoto\u2019s thyroiditis and hypothyroidism","volume":"44","author":"Nemr R.","year":"1996","journal-title":"Journal Medical Libanais. Lebanese Medical Journal"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2265.2011.04302.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2265.2011.04302.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T11:43:05Z","timestamp":1698752585000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2265.2011.04302.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,5]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["10.1111\/j.1365-2265.2011.04302.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2265.2011.04302.x","archive":["Portico"],"relation":{},"ISSN":["0300-0664","1365-2265"],"issn-type":[{"value":"0300-0664","type":"print"},{"value":"1365-2265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,5]]}}}