{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T01:47:23Z","timestamp":1768441643171,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,3,21]],"date-time":"2006-03-21T00:00:00Z","timestamp":1142899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> Fine needle aspiration cytology (FNAC) of lymph nodes can be used routinely as a first\u2010line diagnostic test. The majority of studies reveal a malignant cause for palpable supraclavicular lymph nodes. The present audit further emphasizes the use of FNAC as a first\u2010line investigation for the evaluation of enlarged supraclavicular lymph nodes.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> A total of 200 cases of palpable supraclavicular lymph node(s) were included in the present study.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Left supraclavicular lymph nodes were found to be more commonly involved (59.5% cases). Sixty\u2010four per cent cases showed metastatic deposits and 13.5% cases were diagnosed as tuberculosis. Ten per cent cases showed reactive lymphoid hyperplasia; 0.5% (one) case showed only necrosis and on autopsy, a microscopic focus of choriocarcinoma was found in the testis. In 7.5% cases, diagnostic material could not be aspirated despite repeated attempts. Common metastatic tumours were from lung (22% cases), breast (16.4% cases), cervix (11% cases) and oesophagus (8.6% cases). In 13.3% cases the primary site was unknown and the diagnosis of malignancy first came from FNAC.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The present study further highlights the importance of FNAC as a first\u2010line diagnostic modality in the evaluation of supraclavicular lymphadenopathy. A full history, radiological findings and immunochemistry in difficult cases can help to arrive at a definitive diagnosis.<\/jats:p>","DOI":"10.1111\/j.1365-2303.2006.00285.x","type":"journal-article","created":{"date-parts":[[2006,3,21]],"date-time":"2006-03-21T10:02:26Z","timestamp":1142935346000},"page":"94-96","source":"Crossref","is-referenced-by-count":20,"title":["Pathology of supraclavicular lymphadenopathy in Chandigarh, north India: an audit of 200 cases diagnosed by needle aspiration"],"prefix":"10.1111","volume":"17","author":[{"given":"N.","family":"Gupta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rajwanshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Nijhawan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,3,21]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2303.2003.00057.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2303.2003.00030.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/000313489906500809"},{"key":"e_1_2_5_5_2","first-page":"727","article-title":"Virchow's node revisited: analysis with clinicopathologic correlation of 152 fine\u2010needle aspiration biopsies of supraclavicular lymph nodes","volume":"119","author":"Cervin JR","year":"1995","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10002"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1944.01230010114002"},{"key":"e_1_2_5_8_2","first-page":"230","article-title":"Supraclavicular lymph node metastasis from carcinoma of the uterine cervix after radiotherapy: analysis of 219 patients","volume":"10","author":"Yoa ZH","year":"1988","journal-title":"Chung-Hua Chung Liu Tsa Chih"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840030309"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10051"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0339(199604)14:3<216::AID-DC4>3.0.CO;2-F"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2303.2006.00285.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2303.2006.00285.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T21:50:39Z","timestamp":1697233839000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2303.2006.00285.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,21]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1111\/j.1365-2303.2006.00285.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2303.2006.00285.x","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3,21]]}}}