{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T17:43:09Z","timestamp":1757698989903},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,11,27]],"date-time":"2006-11-27T00:00:00Z","timestamp":1164585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytopathology"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> The National Health Service Cervical Screening Programme monitors the quality of colposcopy services through the annual KC65 returns. The 2002 returns demonstrated that Standard 7c, which specifies a biopsy rate \u226590% at first colposcopy visit for high\u2010grade referrals, was not met in the assessed 3\u2010month period. This was investigated along with the other standards.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Retrospective colposcopy records were accessed for the 597 new referrals, excluding 10 pregnant patients, seen at the colposcopy clinic at the Royal Victoria Infirmary between 1 July 2001 and 31 December 2002, following an abnormal high\u2010grade smear. Cytology and histopathology computer records were checked for confirmation. The results were assessed against the colposcopy standards applicable at that time and the revised standards (2004).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Biopsies were taken from 94.47% (Standard \u226590%) of women at index colposcopy visit including wire loop excision biopsies from 66.16% (87.97% of high\u2010grade colposcopic appearances). Cervical intraepithelial neoplasia (CIN) on histology was found in 91.79% in the study group (Standard \u226585%) and in 96.71% of index visit biopsies (Standard \u226590%), meeting the applicable colposcopy standards. The revised 2004 standards specify a biopsy in \u226595% of high\u2010grade referrals and excision biopsies in 95% if colposcopic appearances are also high\u2010grade, if colposcopy is low grade but the smear is severely dyskaryotic, or when the lesion extends into the canal. The positive predictive value of high\u2010grade cytology for this entire group was 75.54% with CIN present in 90.95%.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> From this study it appears that high\u2010grade cytology in this centre reliably indicates high\u2010grade CIN. Therefore, in women referred for colposcopy following a high\u2010grade smear, excision biopsies should be performed in a higher proportion at the first visit to comply with the revised standards.<\/jats:p>","DOI":"10.1111\/j.1365-2303.2006.00395.x","type":"journal-article","created":{"date-parts":[[2006,11,27]],"date-time":"2006-11-27T19:52:31Z","timestamp":1164657151000},"page":"339-347","source":"Crossref","is-referenced-by-count":9,"title":["Colposcopic management of high\u2010grade referral smears: a retrospective audit supporting \u2018see and treat'?"],"prefix":"10.1111","volume":"17","author":[{"given":"C. A.","family":"Errington","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Tindle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Michael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. N.","family":"Bulmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Wadehra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,11,27]]},"reference":[{"key":"e_1_2_7_2_2","volume-title":"Standards & Quality in Colposcopy","author":"Luesley D","year":"1996"},{"key":"e_1_2_7_3_2","volume-title":"Guidelines for Clinical Practice and Programme Management","author":"Duncan ID","year":"1997"},{"key":"e_1_2_7_4_2","volume-title":"Colposcopy and Programme Management. Guidelines for the NHS Cervical Screening Programme","author":"Luesley D","year":"2004"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2303.2003.00047.x"},{"key":"e_1_2_7_6_2","first-page":"223","article-title":"Is default from colposcopy a problem, and if so what we can do? A systematic review of the literature","volume":"49","author":"Wilsons Lester H","year":"1999","journal-title":"Br J Gen Pract"},{"key":"e_1_2_7_7_2","first-page":"715","article-title":"Discrepancy of cervical cytology and colposcopic biopsy: is cervical conization necessary","volume":"77","author":"McCord ML","year":"1991","journal-title":"Obstet Gynaecol"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08082.x"},{"key":"e_1_2_7_9_2","volume-title":"Achievable Standards, Benchmarks for Reporting, and Criteria for Evaluating Cervical Cytopathology","author":"Johnson J","year":"2000"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb10054.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1990.tb02575.x"},{"issue":"6","key":"e_1_2_7_12_2","first-page":"1020","article-title":"Loop electrosurgical excision procedure of the transformation zone and colposcopically directed punch biopsy in the diagnosis of cervical lesions","volume":"80","author":"Bonardi R","year":"1992","journal-title":"Obstet Gynaecol"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2002.01277.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68181-6"}],"container-title":["Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2303.2006.00395.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2303.2006.00395.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:35:46Z","timestamp":1697416546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2303.2006.00395.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,27]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1111\/j.1365-2303.2006.00395.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2303.2006.00395.x","archive":["Portico"],"relation":{},"ISSN":["0956-5507","1365-2303"],"issn-type":[{"value":"0956-5507","type":"print"},{"value":"1365-2303","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,27]]}}}