{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:05:56Z","timestamp":1773389156611,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1756,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1111\/j.1365-2362.2010.02410.x","type":"journal-article","created":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T12:29:18Z","timestamp":1289392158000},"page":"299-307","source":"Crossref","is-referenced-by-count":28,"title":["Autophagy as a mechanism for myolysis of cardiomyocytes in mitral regurgitation"],"prefix":"10.1111","volume":"41","author":[{"given":"Mien-Cheng","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jen-Ping","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Hao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Chun","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsueh-Wen","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,11,10]]},"reference":[{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cardfail.2003.12.006","article-title":"Mitral regurgitation in patients with advanced systolic heart failure","volume":"10","author":"Patel","year":"2004","journal-title":"J Card Fail"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/S0002-9149(02)03301-5","article-title":"Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure","volume":"91","author":"Trichon","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.carpath.2007.07.008","article-title":"Dedifferentiation of atrial cardiomyocytes in cardiac valve disease: unrelated to atrial fibrillation","volume":"17","author":"Chen","year":"2008","journal-title":"Cardiovasc Pathol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.amjcard.2008.05.038","article-title":"Increased inflammatory cell infiltration in the atrial myocardium of patients with atrial fibrillation","volume":"102","author":"Chen","year":"2008","journal-title":"Am J Cardiol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"13807","DOI":"10.1073\/pnas.0506843102","article-title":"Autophagy in chronically ischemic myocardium","volume":"102","author":"Yan","year":"2005","journal-title":"PNAS"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB6|cit6","article-title":"DNA repair in TUNEL-positive atrial cardiomyocytes of mitral and tricuspid valve diseases: potential mechanism for preserving cardiomyocytes","author":"Chang","year":"2009","journal-title":"Int J Cardiol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"5720","DOI":"10.1093\/emboj\/19.21.5720","article-title":"LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing","volume":"19","author":"Kabeya","year":"2000","journal-title":"EMBO J"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"29278","DOI":"10.1074\/jbc.M303800200","article-title":"Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B","volume":"278","author":"He","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/nature06639","article-title":"Autophagy fights disease through cellular self-digestion","volume":"451","author":"Mizushima","year":"2008","journal-title":"Nature"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4161\/auto.5338","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes","volume":"4","author":"Klionsky","year":"2008","journal-title":"Autophagy"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1136\/jcp.49.1.34","article-title":"Detection of myocardial infarction by immunohistological staining for C9 on formalin fixed, paraffin wax embedded sections","volume":"49","author":"Doran","year":"1996","journal-title":"J Clin Pathol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1161\/01.CIR.96.9.3157","article-title":"Structural changes of atrial myocardium due to sustained atrial fibrillation in the goat","volume":"96","author":"Ausma","year":"1997","journal-title":"Circulation"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cell.2007.12.018","article-title":"Autophagy in the pathogenesis of disease","volume":"132","author":"Levine","year":"2008","journal-title":"Cell"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB14|cit14","article-title":"Atrial myocardial nox2 containing NADPH oxidase activity contribution to oxidative stress in mitral regurgitation: potential mechanism for atrial remodeling","author":"Chang","year":"2010","journal-title":"Cardiovasc Pathol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.clinbiochem.2009.04.012","article-title":"Increased serum oxidative stress in patients with severe mitral regurgitation: a new finding and potential mechanism for atrial enlargement","volume":"42","author":"Chen","year":"2009","journal-title":"Clin Biochem"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1016\/j.humpath.2007.12.007","article-title":"Heme oxygenase-1 expression in the left atrial myocardium of patients with chronic atrial fibrillation related to mitral valve disease: its regional relationship with structural remodeling","volume":"39","author":"Corradi","year":"2008","journal-title":"Hum Pathol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/ajh.20294","article-title":"Hydroxychloroquine causes severe vacuolar myopathy in a patient with chronic graft-versus-host disease","volume":"78","author":"Bolanos-Meade","year":"2005","journal-title":"Am J Hematol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S1534-5807(04)00099-1","article-title":"Development by self-digestion: molecular mechanisms and biological functions of autophagy","volume":"6","author":"Levine","year":"2004","journal-title":"Dev Cell"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/nrm1660","article-title":"Autophagy in metazoans: cell survival in the land of plenty","volume":"6","author":"Lum","year":"2005","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0896-6273(03)00601-9","article-title":"Diversity in the mechanisms of neuronal cell death","volume":"40","author":"Yuan","year":"2003","journal-title":"Neuron"},{"issue":"Suppl. 2","key":"10.1111\/j.1365-2362.2010.02410.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1038\/sj.cdd.4401777","article-title":"Another way to die: autophagic programmed cell death","volume":"12","author":"Tsujimoto","year":"2005","journal-title":"Cell Death Differ"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1016\/j.jacc.2004.02.053","article-title":"Human hibernating myocardium is jeopardized by apoptotic and autophagic cell death","volume":"43","author":"Elsasser","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1172\/JCI27523","article-title":"Cardiac autophagy is a maladaptive response to hemodynamic stress","volume":"117","author":"Zhu","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1365-2362.2010.02410.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"542","DOI":"10.4161\/auto.4600","article-title":"How to interpret LC3 immunoblotting","volume":"3","author":"Mizushima","year":"2007","journal-title":"Autophagy"}],"container-title":["European Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2362.2010.02410.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2362.2010.02410.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T01:13:49Z","timestamp":1625361229000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2362.2010.02410.x"}},"subtitle":["AUTOPHAGY IN MITRAL AND TRICUSPID REGURGITATION"],"short-title":[],"issued":{"date-parts":[[2010,11,10]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2362.2010.02410.x","relation":{},"ISSN":["0014-2972"],"issn-type":[{"value":"0014-2972","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11,10]]}}}