{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:25:43Z","timestamp":1771046743340,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,11,21]],"date-time":"2011-11-21T00:00:00Z","timestamp":1321833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p><jats:bold>Summary.\u2002<\/jats:bold> End\u2010stage haemophiliac arthropathy can be successfully treated with total knee arthroplasty. However, the functional results may not be as good as anticipated and certain pre\u2010op knee characteristics may alter the functional results. The purpose of this study was to evaluate the functional outcome of TKA in haemophilic patients with specific attention to final range of motion and residual flexion contracture of the joint. Twenty\u2010one consecutive patients were retrospectively reviewed. The average age was 34\u2003years with an average follow\u2010up of 5.7\u2003years. Functional status was evaluated with Hospital for Special Surgery Knee Score. Receiving Operating Characteristics analysis was used to determine the threshold of pre\u2010operative flexion contracture degree to avoid residual knee contracture. The range of motion was increased in 16 joints and unchanged in three joints and decreased in the remaining two. Preoperative average range of motion was 37.6\u00b0, improved to 57.1\u00b0 post\u2010operatively. The average knee score increased from 27.85 (15\u201330) points pre\u2010operatively to 79.42 (12\u201394) points at the last follow\u2010up. The degree of pre\u2010operative flexion contracture was found to be a good predictor for residual flexion contracture. (Specificity: 85.7%, sensitivity: 100%, cut\u2010off: 27.5\u00b0). Total knee replacement improves the quality of life in patients with advanced haemophilic arthropathy. Statistical analysis revealed that pre\u2010op flexion contracture of 27.5\u00b0 is an important threshold. Patients should be operated before that stage to gain maximum benefit with minimal gait abnormalities.<\/jats:p>","DOI":"10.1111\/j.1365-2516.2011.02695.x","type":"journal-article","created":{"date-parts":[[2011,11,22]],"date-time":"2011-11-22T04:53:35Z","timestamp":1321937615000},"page":"358-363","source":"Crossref","is-referenced-by-count":35,"title":["Pre\u2010operative flexion contracture determines the functional outcome of haemophilic arthropathy treated with total knee arthroplasty"],"prefix":"10.1111","volume":"18","author":[{"given":"B.","family":"ATILLA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"CAGLAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"PEKMEZCI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"BUYUKASIK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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