{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T20:36:00Z","timestamp":1761510960545},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,3,8]],"date-time":"2012-03-08T00:00:00Z","timestamp":1331164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p><jats:bold>Summary.\u2002<\/jats:bold> Children with haemophilia often bleed inside joints and muscles, which may impair postural adjustments. These postural adjustments are necessary to control postural balance during daily activities. The inability to quickly recover postural balance could elevate the risk of bleeding. To determine whether children with haemophilia have impaired postural adjustment after an unexpected perturbation compared with healthy children. Twenty children with haemophilia comprised the haemophilic group (HG), and 20 healthy, age\u2010paired children comprised the control group (CG). Subjects stood on a force plate, and 4% of the subjects\u2019 body weight was applied via a pulley system to a belt around the subjects\u2019 trunks. The centre of pressure (COP) displacement was measured after the weight was unexpectedly released to produce a controlled postural perturbation followed by postural adjustment to recover balance. The subjects\u2019 postural adjustments in eight subsequent intervals of 1\u2003s (<jats:italic>t<\/jats:italic>1\u2013<jats:italic>t<\/jats:italic>8), beginning with the moment of weight removal, were compared among intervals and between groups. The applied perturbation magnitudes were the same for both groups, and no difference was observed between the groups in <jats:italic>t<\/jats:italic>1. However, the COP displacement in <jats:italic>t<\/jats:italic>2 in the HG was significantly higher than in the CG. No differences were observed between the groups in the other intervals. Within\u2010group analysis showed that the COP was higher in <jats:italic>t<\/jats:italic>2 than in <jats:italic>t<\/jats:italic>4 (<jats:italic>P<\/jats:italic>\u2003=\u20030.016), <jats:italic>t<\/jats:italic>5 (<jats:italic>P<\/jats:italic>\u2003=\u20030.001) and <jats:italic>t<\/jats:italic>8 (<jats:italic>P<\/jats:italic>\u2003=\u20030.050) in the HG. No differences were observed among intervals in the CG. Children with haemophilia demonstrated differences in postural adjustment while undergoing unexpected balance perturbations when compared with healthily children.<\/jats:p>","DOI":"10.1111\/j.1365-2516.2012.02768.x","type":"journal-article","created":{"date-parts":[[2012,3,8]],"date-time":"2012-03-08T09:16:29Z","timestamp":1331198189000},"source":"Crossref","is-referenced-by-count":16,"title":["Postural adjustment after an unexpected perturbation in children with haemophilia"],"prefix":"10.1111","volume":"18","author":[{"given":"F. M. B.","family":"De SOUZA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. P.","family":"PEREIRA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. P.","family":"MINUQUE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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