{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:51:17Z","timestamp":1783529477760,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,5,30]],"date-time":"2012-05-30T00:00:00Z","timestamp":1338336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Since normative surface <jats:styled-content style=\"fixed-case\">EMG (SEMG)<\/jats:styled-content> values for muscles acting at the knee joint are available for people with haemophilia, increasing interest is noticeable for other joints affected by haemophilic arthropathy. Adequate activity of shank muscles is an important key for appropriate postural control. The aim of this study was to determine differences in muscle activation patterns of lower leg muscles between people with and without haemophilia during upright standing. <jats:styled-content style=\"fixed-case\">SEMG<\/jats:styled-content> of tibialis anterior (<jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>), fibularis longus (<jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>), lateral (<jats:styled-content style=\"fixed-case\">LG<\/jats:styled-content>) and medial (<jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>) heads of gastrocnemius, and soleus (<jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content>) muscles of both sides were recorded in 25 haemophilic patients (H) and 25 non\u2010haemophilic control subjects (C) while standing on even ground. The Gilbert\u2010Score was used to assign sides to major (H\u2010<jats:styled-content style=\"fixed-case\">MA<\/jats:styled-content>) and minor (H\u2010<jats:styled-content style=\"fixed-case\">MI<\/jats:styled-content>) affected ankle joints in H. To normalize the <jats:styled-content style=\"fixed-case\">SEMG<\/jats:styled-content> amplitudes, amplitude ratios (percentage of cumulated activity) were calculated. Compared to controls, <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> ratios showed higher and <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> reduced levels in both H groups (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.01). In the H\u2010<jats:styled-content style=\"fixed-case\">MA<\/jats:styled-content> subgroup of H, <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> also joined the <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> behaviour whereas <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content> had similar activation direction as <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>. Although possible descending influences from the knee joints cannot be excluded, this can be interpreted as a compensational mechanism due to the severity of the orthopaedic status of the ankle, which with increasing heaviness is accompanied by reduced plantar flexion capability. However, ankle joint integrity appears to be reduced in H, with <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> seeming to play key roles for neuromuscular control of upright posture.<\/jats:p>","DOI":"10.1111\/j.1365-2516.2012.02852.x","type":"journal-article","created":{"date-parts":[[2012,5,30]],"date-time":"2012-05-30T04:51:14Z","timestamp":1338353474000},"page":"948-954","source":"Crossref","is-referenced-by-count":21,"title":["Ankle muscle activation in people with haemophilia"],"prefix":"10.1111","volume":"18","author":[{"given":"E.","family":"Kurz","sequence":"first","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal Wuppertal Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Anders","sequence":"additional","affiliation":[{"name":"Division for Motor Research, Pathophysiology and Biomechanics Clinic for Trauma, Hand and Reconstructive Surgery University Hospital Jena Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Herbsleb","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine and Health Promotion Friedrich\u2010Schiller\u2010University Jena Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Puta","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine and Health Promotion Friedrich\u2010Schiller\u2010University Jena Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Czepa","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal Wuppertal Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Hilberg","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal Wuppertal Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067659"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2006.01285.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2008.01867.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(96)00170-4"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-2-199707150-00001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2006.01214.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.1998.440528.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2003.00679.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-73535-9_7"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110079301400407"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2010.02399.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-07-0492"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2010.02466.x"},{"key":"e_1_2_9_15_1","first-page":"3","article-title":"Prophylaxis: musculoskeletal evaluation","volume":"30","author":"Gilbert MS","year":"1993","journal-title":"Semin Hematol"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2001.00563.x"},{"key":"e_1_2_9_17_1","volume-title":"SENIAM 8. 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