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Mucosal and mural causes of malabsorption are abundant, and include gluten\u2010sensitive enteropathy, tropical sprue, autoimmune enteropathy, and HIV\/AIDS\u2010related enteropathy, as well as mural conditions such as systemic sclerosis. Finally, microbial causes of malabsorption include bacterial overgrowth, Whipple's disease, and numerous infections or infestations that are most frequently seen in immunocompromised patients. An overview of the most common and interesting entities in each of these categories follows, along with a discussion of current concepts. 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