{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:20:05Z","timestamp":1788412805687,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T00:00:00Z","timestamp":1330387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Histopathology"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>\n                    Chiosea S I, Griffith C, Assaad A &amp; Seethala R R \u2028(2012)\n                    <jats:italic>Histopathology<\/jats:italic>\n                    \u00a0\n                    <jats:bold>61,<\/jats:bold>\n                    387\u2013394\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Clinicopathological characterization of mammary analogue secretory carcinoma of salivary glands<\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Aims:\u2002<\/jats:bold>\n                    Mammary analogue secretory carcinoma (MASC) is a recently described tumour with\n                    <jats:italic>ETV6<\/jats:italic>\n                    translocation. We aimed to characterize the clinical significance of recognizing MASC.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods and results:\u2002<\/jats:bold>\n                    Thirty\u2010six patients with MASC (27 identified retrospectively and nine prospectively) are presented. Historically, MASC mimicked other salivary tumours, as follows: 14 of 37 (37.8%) adenocarcinoma, not otherwise specified, 11 of 89 (12.4%) acinic cell carcinomas (AciCC), one of five (20%) mucin\u2010producing signet ring adenocarcinomas, and one of 165 (0.6%) mucoepidermoid carcinomas. Demographically, MASC affected males more commonly (1.4:1). The average age at diagnosis was 45.7\u2003years. Parotid gland was the most common site of involvement (26 of 36, 72.2%), although other head and neck sites, including the base of tongue, were affected. Of 18 patients with neck dissection, lymph node involvement was identified in four patients (four of 18, 22.2%). Survival analysis of MASC cases presented here, combined with those reported previously, revealed a mean disease\u2010free survival for patients with MASC of 92\u2003months [\n                    <jats:italic>n\u2003<\/jats:italic>\n                    =\n                    <jats:italic>\u2003<\/jats:italic>\n                    29; 95% confidence interval (CI) 71\u2013115\u2003months], compared with a mean DFS of 121\u2003months for patients with AciCC (\n                    <jats:italic>n\u2003<\/jats:italic>\n                    =\n                    <jats:italic>\u2003<\/jats:italic>\n                    38; 95% CI 92\u2013149,\n                    <jats:italic>P\u2003<\/jats:italic>\n                    =\n                    <jats:italic>\u2003<\/jats:italic>\n                    0.43).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:\u2002<\/jats:bold>\n                    Although perhaps slightly more aggressive, MASC clinical outcome mimics that of AciCC.\n                  <\/jats:p>","DOI":"10.1111\/j.1365-2559.2012.04232.x","type":"journal-article","created":{"date-parts":[[2012,2,28]],"date-time":"2012-02-28T09:56:26Z","timestamp":1330422986000},"page":"387-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":224,"title":["Clinicopathological characterization of mammary analogue secretory carcinoma of salivary glands"],"prefix":"10.1111","volume":"61","author":[{"given":"Simion I","family":"Chiosea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Griffith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"Assaad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja R","family":"Seethala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,2,28]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181d9efcc"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00180-0"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0298-184"},{"key":"e_1_2_8_5_2","first-page":"5046","article-title":"ETV6\u2013NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma","volume":"58","author":"Knezevich SR","year":"1998","journal-title":"Cancer 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