{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:55:07Z","timestamp":1767851707788,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2006,6,16]],"date-time":"2006-06-16T00:00:00Z","timestamp":1150416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> To discuss a rare, but severe complication arising following routine root canal treatment.<\/jats:p><jats:p><jats:bold>Summary\u2002<\/jats:bold> An orbital abscess is reported that occurred following routine root canal treatment. A young, healthy female patient, with no history of chronic paranasal infection had undergone root canal treatment of the right maxillary first molar. On hospital admission, she presented with extensive periorbital swelling and discreet diplopia. Computed tomography imaging identified massive purulent sinusitis and subsequent involvement of the orbit via the inferior and medial orbital wall within 48\u2003h after completion of root canal treatment. Immediate surgical drainage of the maxillary sinus and the orbit was established and a high dose of perioperative antibiotics (Amoxicillin\/Clavulanic acid, Gentamycin, Metronidazole) were administered. Vision remained undisturbed and mobility of the globe recovered within 10\u2003days.<\/jats:p><jats:p><jats:bold>Key learning points<\/jats:bold> \u2022\u2002Rapid exacerbation of a periapical inflammation may occur following root canal treatment and may even involve the orbit.<\/jats:p><jats:p>\u2022\u2002A typical speed of disease progression or ophthalmic symptoms should alert the clinician to at least consider unusual early orbital spread of odontogenic infection.<\/jats:p><jats:p>\u2022\u2002When extra\u2010alveolar spread and especially orbital spread is suspected, immediate referral to a maxillofacial or other specialized unit is mandatory.<\/jats:p>","DOI":"10.1111\/j.1365-2591.2006.01130.x","type":"journal-article","created":{"date-parts":[[2006,6,16]],"date-time":"2006-06-16T15:04:56Z","timestamp":1150470296000},"page":"657-664","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Abscess of the orbit arising 48\u2003h after root canal treatment of a maxillary first molar"],"prefix":"10.1111","volume":"39","author":[{"given":"F.","family":"Koch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Breil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. B.","family":"Marroqu\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Gawehn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kunkel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,7]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"268","article-title":"Orbital abscess of odontogenic origin","volume":"20","author":"Allan BP","year":"1991","journal-title":"Journal of Maxillofacial Surgery"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2003.00662.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.1991.tb00464.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(85)90328-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200405000-00002"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.66.4.269"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-1546.2002.20105.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200312000-00001"},{"key":"e_1_2_6_10_1","first-page":"40","article-title":"Pansinusitis, orbital cellulitis, and blindness as sequelae of decayed treatment of dental abscess","volume":"32","author":"Gold RS","year":"1974","journal-title":"Journal of Oral Surgery"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1971.0324"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1983.01040010751010"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(92)90365-7"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(67)90138-7"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(84)90202-9"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2890090406"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1969.00990010685013"},{"key":"e_1_2_6_18_1","first-page":"682","article-title":"Orbital cellulitis of dental origin: differential diagnosis and the use of computed tomography as a diagnostic aid","volume":"38","author":"Kaban LB","year":"1980","journal-title":"Journal of Oral Surgery"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1980.01020030270004"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(82)34763-6"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310015380"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(88)90336-9"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2004.00122.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1980.0280"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(92)90386-5"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2003.00671.x"}],"container-title":["International Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2591.2006.01130.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2591.2006.01130.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T01:13:43Z","timestamp":1697332423000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2591.2006.01130.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,7]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["10.1111\/j.1365-2591.2006.01130.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2591.2006.01130.x","archive":["Portico"],"relation":{},"ISSN":["0143-2885","1365-2591"],"issn-type":[{"value":"0143-2885","type":"print"},{"value":"1365-2591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,7]]},"assertion":[{"value":"2006-07-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}