{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:14:34Z","timestamp":1790486074958,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,11,14]],"date-time":"2011-11-14T00:00:00Z","timestamp":1321228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:sec><jats:label\/><jats:p><jats:bold>Didilescu AC, Rusu D, Anghel A, Nica L, Iliescu A, Greabu M, Bancescu G, Stratul SI.<\/jats:bold> Investigation of six selected bacterial species in endo\u2010periodontal lesions. <jats:italic>International Endodontic Journal<\/jats:italic>, <jats:bold>45<\/jats:bold>, 282\u2013293, 2012.<\/jats:p><\/jats:sec><jats:sec><jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> To investigate and determine possible associations of six tested bacteria belonging to \u2018orange\u2019 and \u2018green\u2019 complexes, in endo\u2010periodontal lesions: <jats:italic>Parvimonas micra, Fusobacterium nucleatum, Campylobacter rectus, Eubacterium nodatum, Eikenella corrodens<\/jats:italic> and <jats:italic>Capnocytophaga sputigena<\/jats:italic>.<\/jats:p><jats:p><jats:bold>Methodology\u2002<\/jats:bold> Forty\u2010six patients presenting with different types of endo\u2010periodontal lesions were investigated. Clinical examinations, periapical radiographs and microbiological sampling from the canal system (endo) and periodontal pockets (perio) were performed. Qualitative and semiquantitative evaluation of bacteria was performed by polymerase chain reaction (PCR) and DNA\u2013DNA hybridization (micro\u2010IDent <jats:italic>plus<\/jats:italic>; Hain Lifescience, Germany).<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> Extremely high bacterial loads in endodontic samples were recorded for <jats:italic>P.\u00a0micra<\/jats:italic>, <jats:italic>F.\u00a0nucleatum<\/jats:italic> and <jats:italic>C.\u00a0sputigena<\/jats:italic>, while periodontal samples were often colonized by the same species, plus <jats:italic>C.\u00a0rectus<\/jats:italic>. Significant association was recorded between <jats:italic>F.\u00a0nucleatum<\/jats:italic>\u2010endo and <jats:italic>P.\u00a0micra<\/jats:italic>\u2010endo (<jats:italic>P\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.03, Fisher\u2019s exact test). There was marginal evidence of associations between: (i) <jats:italic>C.\u00a0sputigena<\/jats:italic>\u2010endo and <jats:italic>C.\u00a0sputigena<\/jats:italic>\u2010perio (<jats:italic>P\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.06, Fisher\u2019s exact test); (ii) <jats:italic>P.\u00a0micra<\/jats:italic>\u2010endo and <jats:italic>P.\u00a0micra<\/jats:italic>\u2010perio (<jats:italic>P\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.05, Fisher\u2019s exact test). Sensitivity to percussion was associated with an increased chance of cases with <jats:italic>P.\u00a0micra<\/jats:italic>\u2010endo (<jats:italic>P\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.03, Pearson chi\u2010square test).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> The findings suggest that <jats:italic>F.\u00a0nucleatum<\/jats:italic>, <jats:italic>P.\u00a0micra<\/jats:italic> and <jats:italic>C.\u00a0sputigena<\/jats:italic> may play a role in the pathogenesis of endo\u2010periodontal lesions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1365-2591.2011.01974.x","type":"journal-article","created":{"date-parts":[[2011,11,14]],"date-time":"2011-11-14T07:25:53Z","timestamp":1321255553000},"page":"282-293","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Investigation of six selected bacterial species in endo\u2010periodontal lesions"],"prefix":"10.1111","volume":"45","author":[{"given":"A. 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