{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T10:50:10Z","timestamp":1771930210203,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"s2","license":[{"start":{"date-parts":[[2005,10,18]],"date-time":"2005-10-18T00:00:00Z","timestamp":1129593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J of Andrology"],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A number of disease processes of the penis including Peyronie's disease, priapism, penile fractures and tumors are clearly visualized with ultrasound. Diagnostic evaluation of erectile dysfunction (ED) by penile dynamic colour\u2010duplex Doppler ultrasonography (D\u2010CDDU) is actually considered a second level approach to ED patients because of the fact that intracavernous injections test IV with prostaglandin\u2010E<jats:sub>1<\/jats:sub> may provide important information about the patients\u2019 erectile capacity. However, no direct vascular imaging and a high percentage of false negative diagnoses of vasculogenic ED are its major pitfalls and subsequent treatment decisions remain quite limited. The occurrence of ED and its sentinel relationship to cardiovascular disease has prompted more accurate vascular screening in all patients even in the absence of cardiovascular risk factors. The sonographic evaluation of the intima\u2010media thickness of the carotid arteries may sometimes represent an early manifestation of diffuse atherosclerotic disease and endothelial damage. This latter finding is often the cause of failure to oral agents, i.e. phosphodiesterase inhibitors, because of inability of the dysfunctional endothelium to release nitric oxide. D\u2010CDDU represents an accurate tool to investigate cavernous artery inflow and venous leakage when compared with more invasive diagnostic techniques i.e. selective arteriography and dynamic infusion cavernosometry along with cavernosography.<\/jats:p>","DOI":"10.1111\/j.1365-2605.2005.00587.x","type":"journal-article","created":{"date-parts":[[2005,10,18]],"date-time":"2005-10-18T15:26:03Z","timestamp":1129649163000},"page":"61-63","source":"Crossref","is-referenced-by-count":44,"title":["Diagnosing Erectile Dysfunction: The penile dynamic colour duplex ultrasound revisited"],"prefix":"10.1111","volume":"28","author":[{"given":"A.","family":"AVERSA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"BRUZZICHES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"SPERA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,18]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-004-0423-y"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.1996.tb00481.x"},{"key":"e_1_2_3_4_1","first-page":"499","article-title":"The use of dynamic Doppler color ultrasonography of the penis in the study of erectile dysfunction","volume":"97","author":"Aversa A.","year":"1999","journal-title":"Radiologia Medica"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3900477"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2605.2002.00314.x"},{"key":"e_1_2_3_7_1","first-page":"38","article-title":"Non\u2010invasive vascular imaging in the diagnosis of erectile dysfunction","volume":"25","author":"Aversa A.","year":"2003","journal-title":"Journal of Endocrinological Investigation"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000116325.06572.85"},{"key":"e_1_2_3_9_1","first-page":"233","volume-title":"Textbook of Erectile Dysfunction","author":"Broderick G. A.","year":"1999"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.03.016"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000124323.02868.68"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1994.13.8.591"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3900346"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2005.20110.x"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3900704"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64071-2"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(03)00112-0"}],"container-title":["International Journal of Andrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2605.2005.00587.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2605.2005.00587.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T08:57:25Z","timestamp":1695718645000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2605.2005.00587.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10,18]]},"references-count":16,"journal-issue":{"issue":"s2","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["10.1111\/j.1365-2605.2005.00587.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2605.2005.00587.x","archive":["Portico"],"relation":{},"ISSN":["0105-6263","1365-2605"],"issn-type":[{"value":"0105-6263","type":"print"},{"value":"1365-2605","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10,18]]}}}