{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T06:26:37Z","timestamp":1794464797577,"version":"4.9.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,9,23]],"date-time":"2011-09-23T00:00:00Z","timestamp":1316736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p><jats:italic>International Journal of Paediatric Dentistry 2012; 22: 217\u2013227<\/jats:italic><\/jats:p><jats:p><jats:bold>Objective.\u2002<\/jats:bold>To evaluate the clinical and radiographic success rates of three mixed antibiotics in the non\u2010instrumentation endodontic treatment of primary mandibular molars at 24\u201327\u2003months postoperatively.<\/jats:p><jats:p><jats:bold>Methods.\u2002<\/jats:bold>Eighty cariously involved lower primary molars from 58 children (ages 3\u20138\u2003years) received a 3Mix medicament by non\u2010instrumentation endodontic treatment and were then sealed with glass\u2010ionomer cement and composite resin before permanent restoration with stainless steel crowns. The patients received a clinical and radiographic assessment every 6\u2003months over a 2\u2010year follow\u2010up period with an intra\u2010examiner reliability of 0.83\u20131.00 (\u03ba value).<\/jats:p><jats:p><jats:bold>Results.\u2002<\/jats:bold>In 60 cases at 24\u2010 to 27\u2010month follow\u2010up, the success rates as determined by clinical and radiographic evaluation were 75% and 36.7%, respectively; however, the overall success rate of 3Mix non\u2010instrumentation endodontic treatment was 36.7% with 15.8% of cases demonstrating a pulpal response of internal resorption.<\/jats:p><jats:p><jats:bold>Conclusions.\u2002<\/jats:bold>Non\u2010instrumentation endodontic treatment using 3Mix\u2010MP showed good clinical success but had a low success rate based on radiographic evaluation at 2\u2010year follow\u2010up. Hence, 3Mix antibiotic treatment cannot replace a conventional root canal treatment agent as a long\u2010term therapy.<\/jats:p>","DOI":"10.1111\/j.1365-263x.2011.01181.x","type":"journal-article","created":{"date-parts":[[2011,9,27]],"date-time":"2011-09-27T20:25:19Z","timestamp":1317155119000},"page":"217-227","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Success rates of a mixture of ciprofloxacin, metronidazole, and minocycline antibiotics used in the non\u2010instrumentation endodontic treatment of mandibular primary molars with carious pulpal involvement"],"prefix":"10.1111","volume":"22","author":[{"given":"CHUTIMA","family":"TRAIRATVORAKUL","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PALINEE","family":"DETSOMBOONRAT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,9,23]]},"reference":[{"key":"e_1_2_8_2_2","first-page":"144","article-title":"Guildeline on pulp therapy for primary and young permanent teeth. 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