{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:05:42Z","timestamp":1777500342924,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T00:00:00Z","timestamp":1335484800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Paed Dentistry"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:p>\n<jats:italic>International Journal of Paediatric Dentistry 2013; 23: 166\u2013172<\/jats:italic>\n<\/jats:p><jats:p><jats:bold>Objective.\u2002<\/jats:bold> Our <jats:italic>in vitro<\/jats:italic> study evaluated calcium fluoride formation in enamel and the anticaries effect of seven resin\u2010based varnishes under cariogenic challenge.<\/jats:p><jats:p><jats:bold>Methods.\u2002<\/jats:bold> Enamel blocks were subjected to pH cycling. The experimental groups received fluoride varnish application, the positive control received topical fluoride gel treatment, and the negative control did not receive any treatment. The pH cycling surface hardness (SH<jats:sub>1<\/jats:sub>) and integrated loss of subsurface hardness (\u0394KHN) were then determined. We measured the amount of fluoride released into the demineralizing and remineralizing (DE\u2013RE) solutions used in pH cycling. The fluoride concentration in the enamel was determined 24\u2003h after application of the products as loosely bound fluoride and firmly bound fluoride.<\/jats:p><jats:p><jats:bold>Results.\u2002<\/jats:bold> Higher deposits of loosely bound fluoride were observed for Duofluorid, followed by Biophat. For Duraphat, Bifluorid, Duraflur, and Duofluorid, no difference was observed in the SH<jats:sub>1<\/jats:sub> and \u0394KHN values, with the lowest mineral loss compared to the other groups. The Bifluorid and Duofluorid groups released high fluoride amounts into the DE\u2013RE, and statistically significant difference was noted between them.<\/jats:p><jats:p><jats:bold>Conclusions.\u2002<\/jats:bold> The anticaries effect showed no correlation with higher deposited fluoride amounts, resin type, or fluoride source.<\/jats:p>","DOI":"10.1111\/j.1365-263x.2012.01240.x","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T09:19:33Z","timestamp":1335518373000},"page":"166-172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Differences in loosely bound fluoride formation and anticaries effect of resin\u2010based fluoride varnishes"],"prefix":"10.1111","volume":"23","author":[{"given":"JORGE R. S.","family":"MAAS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ITALO M. FARACO","family":"JUNIOR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CAROLINA S.","family":"LODI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALBERTO C. B.","family":"DELBEM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,27]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1415-790X2010000100013"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0232"},{"key":"e_1_2_7_4_2","first-page":"1","article-title":"Fluoride varnishes and caries incidence decrease in preschool children: a systematic review","volume":"13","author":"Carvalho DM","year":"2010","journal-title":"Rev Bras Epidemiol"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-263X.2004.00550.x"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2002.0141"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000088189"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572006000200005"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572009000400003"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000261970"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000092232"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000218094"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000196507"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/104454703768247765"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000084808"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2005.10.003"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(75)90023-0"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)84756-1"},{"key":"e_1_2_7_19_2","first-page":"154","article-title":"Uptake of KOH\u2010soluble and KOH\u2010insoluble fluoride in sound human enamel after topical application of a fluoride varnish (Duraphat) or a neutral 2% NaF solution in vitro","volume":"100","author":"Cruz R","year":"1992","journal-title":"Scand J Dent Res"},{"key":"e_1_2_7_20_2","first-page":"304","article-title":"Effects of sodium fluoride solution and varnish with different fluoride concentrations on enamel remineralization in vitro","volume":"96","author":"Sepp\u00e4 L","year":"1988","journal-title":"Scand J Dent Res"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(95)98804-8"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2001.0053"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572009000300009"}],"container-title":["International Journal of Paediatric Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-263X.2012.01240.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-263X.2012.01240.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T18:45:10Z","timestamp":1698691510000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-263X.2012.01240.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,27]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1111\/j.1365-263X.2012.01240.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-263x.2012.01240.x","archive":["Portico"],"relation":{},"ISSN":["0960-7439","1365-263X"],"issn-type":[{"value":"0960-7439","type":"print"},{"value":"1365-263X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,27]]},"assertion":[{"value":"2012-04-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}