{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T12:34:50Z","timestamp":1789389290354,"version":"build-2803163510"},"reference-count":118,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T00:00:00Z","timestamp":1183161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p><jats:bold>Aims and objectives.\u2002<\/jats:bold>This paper reviews the literature concerning nurses\u2019 assessment and management of pain in adult patients with chronic kidney disease, and proposes implications for clinical practice to support the control of pain in these patients.<\/jats:p><jats:p><jats:bold>Background.\u2002<\/jats:bold>Chronic kidney disease is a worldwide public health concern with increasing incidence and prevalence, poor patient outcomes and high cost. Patients with kidney disease often experience pain. Optimal pain assessment and management are key clinical activities; however, inadequate pain control by health professionals persists. Renal failure compounds this problem because of the small margin between pain relief and toxicity, and the patient's concomitant health problems.<\/jats:p><jats:p><jats:bold>Conclusions.\u2002<\/jats:bold>The literature review uses 93 articles that were published in medical\u2010 and other health\u2010related journals, including 12 medical and pharmaceutical studies specifically relating to pain control in adults with kidney disease. Very little research has been conducted on pain in patients with kidney disease prior to requiring dialysis or kidney transplantation for survival. However, past research showed pain is common and analgesics are underprescribed in patients on dialysis in end\u2010stage kidney disease. The review indicates that an interest in nephrotoxicity and analgesic\u2010induced morbidity dominates over an interest in pain relief in patients with kidney disease. Most analgesics are excreted renally or by the liver, and the use of simple analgesics such as paracetamol is cautioned.<\/jats:p><jats:p><jats:bold>Relevance to clinical practice.\u2002<\/jats:bold>Findings from the literature review highlight specific difficulties relating to effective pain control in patients with chronic kidney disease. Research is required to identify and overcome barriers to effective pain management, including the development of specific tools to facilitate interventions that optimize analgesic outcomes in patients with chronic kidney disease.<\/jats:p>","DOI":"10.1111\/j.1365-2702.2007.01994.x","type":"journal-article","created":{"date-parts":[[2007,6,30]],"date-time":"2007-06-30T15:49:57Z","timestamp":1183218597000},"page":"69-81","source":"Crossref","is-referenced-by-count":22,"title":["A structured literature review of pain assessment and management of patients with chronic kidney disease"],"prefix":"10.1111","volume":"17","author":[{"given":"Allison","family":"Williams","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Manias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,6,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2001.08.997"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(04)01107-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200005000-00038"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10414"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03025.x"},{"key":"e_1_2_10_7_1","volume-title":"Drug Prescribing in Renal Failure: Dosing Guidelines for Adults, 4th edn","author":"Aronoff G","year":"1999"},{"key":"e_1_2_10_8_1","volume-title":"Australian Hospital Statistics 2002\u201303","author":"Australian Institute of Health and Welfare","year":"2004"},{"key":"e_1_2_10_9_1","first-page":"191","volume-title":"American Nephrology Nurses\u2019 Association Core Curriculum for Nephrology Nursing, 4th edn","author":"Baer C","year":"2001"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-139X.2002.t01-1-00911.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00658.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra025411"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002800-199801000-00011"},{"key":"e_1_2_10_14_1","first-page":"70","article-title":"Analgesic nephropathy and the use of nonsteroidal anti\u2010inflammatory drugs in renal patients: new insight","volume":"11","author":"Bennett W","year":"1998","journal-title":"Journal of Nephrology"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2002.02409.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1067\/men.2001.116648"},{"key":"e_1_2_10_17_1","first-page":"575","article-title":"Older people in persistent pain: nursing and paramedical staff perceptions and pain management","volume":"41","author":"Blomqvist K","year":"2003","journal-title":"Issues and Innovations in Nursing Practice"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2834.1997.00031.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-172x.2001.00309.x"},{"key":"e_1_2_10_20_1","volume-title":"The Renal Drug Handbook","author":"Bunn R","year":"2004"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.1997.00460.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006199-199505000-00008"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2002.tb04545.x"},{"key":"e_1_2_10_24_1","first-page":"27","volume-title":"Renal Nursing","author":"Chalmers C","year":"2002"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/10935070152596016"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2000.8286"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2003.02972.x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006416-200103000-00008"},{"key":"e_1_2_10_29_1","first-page":"20","article-title":"Pain management at the end of life in a patient with renal failure","volume":"14","author":"Daines P","year":"2004","journal-title":"Cannt Journal"},{"key":"e_1_2_10_30_1","volume-title":"Handbook of Dialysis","author":"Daugirdas J","year":"2001"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1547-5069.2002.00121.x"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2003.08.025"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ackd.2005.03.008"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199803000-00003"},{"key":"e_1_2_10_35_1","first-page":"431","volume-title":"Renal nursing","author":"De Vos J","year":"2002"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000109961.69936.8e"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeh052"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00585-3"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.1995.21040634.x"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002512-199812050-00005"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010323"},{"key":"e_1_2_10_42_1","first-page":"85","article-title":"Chronic pain during dialysis. Pharmacologic therapy and its costs","volume":"51","author":"Fortina F","year":"1999","journal-title":"Minerva Urologica e Nefrologica"},{"key":"e_1_2_10_43_1","volume-title":"Fundamentals of Pharmacology","author":"Galbraith A","year":"2004"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v32.pm9740150"},{"key":"e_1_2_10_45_1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.4037\/ajcc2004.13.2.126","article-title":"Pain assessment and management in critically ill intubated patients: a retrospective study","volume":"13","author":"Gelinas C","year":"2004","journal-title":"American Journal of Critical Care"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2004.00668.x"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612023394917"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1054\/jpai.2003.5"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006416-200401000-00007"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002709900419"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.1999.13.425"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2002.126185"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006199-199807000-00009"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002820-200002000-00009"},{"key":"e_1_2_10_55_1","volume-title":"Classification of Chronic Pain","author":"International Association for the Study of Pain","year":"1994"},{"key":"e_1_2_10_56_1","first-page":"473","article-title":"Nephrology: 3: Safe drug prescribing for patients with renal insufficiency","volume":"166","author":"Kappel J","year":"2002","journal-title":"Canadian Medical Association Journal"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpmn.2000.9294"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041552-199605000-00009"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00645-0"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2002.02429.x"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199732010-00002"},{"key":"e_1_2_10_62_1","first-page":"117","volume-title":"American Nephrology Nurses\u2019 Association Core Curriculum for Nephrology Nursing","author":"Lancaster L","year":"2001"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003281"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.2307\/3471995"},{"key":"e_1_2_10_65_1","first-page":"3","volume-title":"Chronic Illness: Impact and Interventions","author":"Lubkin I","year":"2002"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2003.02977.x"},{"key":"e_1_2_10_67_1","first-page":"64","article-title":"Pain management: documenting the decision making process","volume":"1","author":"Malek C","year":"1996","journal-title":"Nursing Case Management"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2003.02570.x"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-2018.2003.00140.x"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2003.50048"},{"key":"e_1_2_10_71_1","first-page":"64","article-title":"Mysterious calciphylaxis: wounds with eschar \u2013 to debride or not to debride","volume":"50","author":"Martin R","year":"2004","journal-title":"Ostomy Wound Management"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(97)00170-X"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004650-200311000-00002"},{"key":"e_1_2_10_74_1","unstructured":"McDonaldS ExcellL&ShtangeyV(2005a)Method and location of dialysis. Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) annual report Chap.4 1\u201360."},{"key":"e_1_2_10_75_1","unstructured":"McDonaldS ExcellL&ShtangeyV(2005b)New patients commencing treatment in 2004. Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) annual report Chap.2 1\u201343."},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2003.11.005"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.314.7093.1531"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2005.08.010"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2004.04.007"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-2092(06)63812-X"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2001.20730"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0503300306"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2000.3.57"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1800.2004.00230.x"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.4.903"},{"key":"e_1_2_10_86_1","first-page":"918","article-title":"State\u2010specific trends in chronic kidney failure \u2013 United States, 1990\u20132001","volume":"53","author":"Pirtle C","year":"2004","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1067\/mhl.2002.125652"},{"key":"e_1_2_10_88_1","first-page":"340","article-title":"Pain in end stage renal disease","volume":"30","author":"Rehm M","year":"2003","journal-title":"Nephrology Nursing Journal: Journal of the American Nephrology Nurses\u2019 Association"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.3.315"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1300\/J354v18n03_07"},{"key":"e_1_2_10_91_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1046\/j.0265-0215.2000.00806.x","article-title":"High doses of mepivacaine for brachial plexus block in patients with end\u2010stage chronic renal failure: a pilot study","volume":"18","author":"Rodriguez J","year":"2001","journal-title":"European Journal of Anaesthesiology"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2001.01875.x"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.1999.00903.x"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.1998.00620.x"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2003.11.019"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-240X(200008)23:4<334::AID-NUR9>3.0.CO;2-G"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2003.11.003"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0964-3397(03)00027-2"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2005.18218.x"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.2.163"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1191\/0968130201pr183ra"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-6712.2001.00027.x"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199908000-00014"},{"issue":"3","key":"e_1_2_10_104_1","first-page":"40","article-title":"The burden of acute postoperative pain and the potential role of the COX\u20102\u2010specific inhibitors","volume":"42","author":"Stephens J","year":"2003","journal-title":"Rheumatology"},{"key":"e_1_2_10_105_1","first-page":"315","article-title":"Meperidine associated mental status changes in a patient with chronic renal failure","volume":"83","author":"Stock S","year":"1996","journal-title":"Journal of the Florida Medical Association"},{"key":"e_1_2_10_106_1","first-page":"18","article-title":"How to improve quality of life in patients living with end stage renal failure","volume":"1","author":"Tallis K","year":"2005","journal-title":"Renal Society of Australasia Journal"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1067\/men.2000.108402"},{"key":"e_1_2_10_108_1","volume-title":"Renal Nursing \u2013 A Practical Approach","author":"Terrill B","year":"2002"},{"key":"e_1_2_10_109_1","volume-title":"Renal Nursing","author":"Thomas N","year":"2002"},{"key":"e_1_2_10_110_1","author":"United States Renal Data System","year":"2004","journal-title":"USRDS Annual Data Report"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2003.12.8.11276"},{"key":"e_1_2_10_112_1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.0894-0959.2004.17313.x","article-title":"Depression: a common but underrecognised condition associated with end\u2010stage renal disease","volume":"17","author":"Wang P","year":"2004","journal-title":"Seminars in Dialysis"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2001.02006.x"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-200093050-00007"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2005020157"},{"key":"e_1_2_10_116_1","first-page":"136","article-title":"Quality pain management outcomes: the power of place","volume":"4","author":"Wild L","year":"2000","journal-title":"Outcomes Management for Nursing Practice"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2648.2003.02961.x"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2001.02047.x"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2003.09.002"}],"container-title":["Journal of Clinical Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2702.2007.01994.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2702.2007.01994.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T16:14:48Z","timestamp":1708013688000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2702.2007.01994.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,30]]},"references-count":118,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1111\/j.1365-2702.2007.01994.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2702.2007.01994.x","archive":["Portico"],"relation":{},"ISSN":["0962-1067","1365-2702"],"issn-type":[{"value":"0962-1067","type":"print"},{"value":"1365-2702","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,30]]}}}