{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:55:06Z","timestamp":1764996906363},"reference-count":35,"publisher":"Wiley","issue":"7-8","license":[{"start":{"date-parts":[[2011,2,10]],"date-time":"2011-02-10T00:00:00Z","timestamp":1297296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Clinical Nursing"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:p><jats:bold>Aim.\u2002<\/jats:bold> The aim of this study was to determine whether oral glucose could have a pain\u2010relieving effect during the eye examinations that premature neonates undergo in the screening for retinopathy of prematurity.<\/jats:p><jats:p><jats:bold>Background.\u2002<\/jats:bold> Studies have shown that orally administered sweet\u2010tasting solutions reduce signs of pain during painful procedures such as venepuncture and heel sticks on premature and full\u2010term infants. This effect has not yet been proven during the eye examinations for the screening of retinopathy of prematurity.<\/jats:p><jats:p><jats:bold>Design.\u2002<\/jats:bold> Randomised, controlled, double\u2010blind study.<\/jats:p><jats:p><jats:bold>Method.\u2002<\/jats:bold> Thirty infants born before 32\u2003weeks of gestation and\/or weighing &lt;1500\u2003g at birth were randomised to receive 1\u2003ml of either 30% glucose or sterile water before the eye examination. Examinations were videotaped, and the observer was blinded to the intervention. Pain responses were scored using the premature infant pain profile. Heart rate and crying time were also recorded.<\/jats:p><jats:p><jats:bold>Results.\u2002<\/jats:bold> There were no statistically significant differences between the two groups, neither in premature infant pain profile score, heart rate changes nor crying time.<\/jats:p><jats:p><jats:bold>Conclusion.\u2002<\/jats:bold> This study does not support the pain\u2010relieving effect of orally administered glucose during eye examinations in preterm infants.<\/jats:p><jats:p><jats:bold>Relevance to clinical practice.\u2002<\/jats:bold> Oral glucose should not be used as single measure for pain relief during eye examinations of preterm infants. Other comforting and pain\u2010relieving measures should be used.<\/jats:p>","DOI":"10.1111\/j.1365-2702.2010.03529.x","type":"journal-article","created":{"date-parts":[[2011,2,17]],"date-time":"2011-02-17T13:39:36Z","timestamp":1297949976000},"page":"1054-1059","source":"Crossref","is-referenced-by-count":19,"title":["Oral glucose for pain relief during eye examinations for retinopathy of prematurity"],"prefix":"10.1111","volume":"20","author":[{"given":"Emma","family":"Olsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mats","family":"Eriksson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,10]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2749"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2277"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199309001-00035"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-199912000-00006"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000079542"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.087668"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(00)00085-2"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.319.7222.1393"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.1.60"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005237-200601000-00018"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2008.00826.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(99)00018-3"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1E477"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211199"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2005.tb03075.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.6.1053"},{"key":"e_1_2_10_18_1","unstructured":"GradinM LarssonBA LindhV&SelanderB(2003)National guidelines for prevention and treatment of pain in the newborn infant. 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