{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T20:41:03Z","timestamp":1784061663885,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,1,16]],"date-time":"2006-01-16T00:00:00Z","timestamp":1137369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J intellect Disabil Res"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2003<\/jats:bold> Periodontal disease in Down\u2019s syndrome (DS) individuals develops earlier and is more rapid and extensive than in age\u2010matched normal individuals. The present study evaluated a group of DS patients, who had been participating in a 10\u2010year preventive dental programme, for the impact of the programme on their periodontal status.<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> Thirty DS patients (mean age 23.3\u2003\u00b1\u20034\u2003years) were compared with 28 age\u2010matched healthy controls (mean age 22.8\u2003\u00b1\u20035\u2003years). The hygiene level, gingival condition and periodontal status (periodontal probing depth, clinical attachment level and radiographic alveolar bone loss) were determined.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold> In spite of similar oral hygiene and gingival measures, DS patients, as opposed to the control ones, had a severe periodontal disease. The prevalence, extent and severity of periodontitis in the DS group were significantly greater than in the control group. The teeth most commonly and severely affected were the lower central incisors and the upper first molars. DS patients lost significantly more teeth due to periodontitis.<\/jats:p><jats:p><jats:bold>Conclusions\u2003<\/jats:bold> The clinical and radiographic picture found in the present DS group is characteristic of localized aggressive periodontitis. Within the limitations of this study, it seems that the preventive dental programme had no effect on periodontal destruction progression of localized aggressive periodontitis in DS individuals and that impaired oral hygiene plays a relatively minor role in the pathogenesis of this disease. Future controlled studies are needed to assess the effectiveness of different preventive dental programmes in preventing the progression of periodontitis in DS patients.<\/jats:p>","DOI":"10.1111\/j.1365-2788.2006.00794.x","type":"journal-article","created":{"date-parts":[[2006,1,16]],"date-time":"2006-01-16T15:31:23Z","timestamp":1137425483000},"page":"492-500","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["The outcome of a preventive dental care programme on the prevalence of localized aggressive periodontitis in Down\u2019s syndrome 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