{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T06:00:03Z","timestamp":1774677603620,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,2,26]],"date-time":"2012-02-26T00:00:00Z","timestamp":1330214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Intern Med"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p><jats:bold>Abstract.\u2002<\/jats:bold> Grool AM, van der Graaf Y, Visseren FLJ, de Borst GJ, Algra A, Geerlings MI, on behalf of the SMART Study Group (University Medical Center Utrecht, Utrecht, The Netherlands). Self\u2010rated health status as a risk factor for future vascular events and mortality in patients with symptomatic and asymptomatic atherosclerotic disease: the SMART study. <jats:italic>J Intern Med<\/jats:italic> 2012; <jats:bold>272:<\/jats:bold> 277\u2013286.<\/jats:p><jats:p><jats:bold>Objectives.\u2002<\/jats:bold> Lower self\u2010rated health status has been associated with worse prognosis in patients with coronary artery disease (CAD). We investigated the influence of self\u2010rated physical and mental health status on the risk of future vascular events and mortality for various locations of symptomatic atherosclerotic disease and asymptomatic disease.<\/jats:p><jats:p><jats:bold>Design.\u2002<\/jats:bold> Patients with CAD (<jats:italic>n<\/jats:italic>\u2003=\u20032547), cerebrovascular disease (<jats:italic>n<\/jats:italic>\u2003=\u20031061), peripheral arterial disease (PAD; <jats:italic>n<\/jats:italic>\u2003=\u2003648), abdominal aortic aneurysm (AAA; <jats:italic>n<\/jats:italic>\u2003=\u2003272) and asymptomatic atherosclerotic disease (<jats:italic>n<\/jats:italic>\u2003=\u20031933) were followed for a median of 4\u2003years for the occurrence of a new vascular event or death. Self\u2010rated health status was assessed with the Short Form\u201036 physical and mental component summary scales. Cox regression models were used to estimate associations between health status and vascular events and death, adjusted for age, sex, vascular risk factors and intima\u2013media thickness.<\/jats:p><jats:p><jats:bold>Results.\u2002<\/jats:bold> In the total population, lower self\u2010rated physical health status (per 10\u2010point decrease) increased the risk of vascular events [hazard ratio (HR)\u2003=\u20031.37, 95% confidence interval (CI) 1.24\u20131.52], and all\u2010cause (HR\u2003=\u20031.45, 95% CI 1.29\u20131.63) and vascular mortality (HR\u2003=\u20031.40, 95% CI 1.20\u20131.64). A 10\u2010point decrease in mental health status was associated with a modest increase in the risk of vascular events (HR\u2003=\u20031.19, 95% CI 1.08\u20131.32), and all\u2010cause (HR\u2003=\u20031.19, 95% CI 1.05\u20131.34) and vascular mortality (HR\u2003=\u20031.28, 95% CI 1.09\u20131.49). Risk estimates of physical and mental health status were highest in patients with asymptomatic atherosclerotic disease and lowest in those with PAD.<\/jats:p><jats:p><jats:bold>Conclusions.\u2002<\/jats:bold> Poorer self\u2010rated physical and mental health status increases the risk of vascular events and mortality in a broad population of patients with symptomatic and asymptomatic atherosclerotic disease.<\/jats:p>","DOI":"10.1111\/j.1365-2796.2012.02521.x","type":"journal-article","created":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T22:39:20Z","timestamp":1326926360000},"page":"277-286","source":"Crossref","is-referenced-by-count":19,"title":["Self\u2010rated health status as a risk factor for future vascular events and mortality in patients with symptomatic and asymptomatic atherosclerotic disease: the SMART study"],"prefix":"10.1111","volume":"272","author":[{"given":"A. 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I.","family":"Geerlings","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the SMART Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,2,26]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/3218"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000173836"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1353\/dem.2010.0005"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199912000-00006"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.2307\/2955359"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.11.1274"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.14.1298"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-200211000-00010"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000020688.24874.90"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.12.012"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.09.020"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.48.4.331"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-3-200102060-00014"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJR.0b013e3283361ce6"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007621514757"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_8_18_2","volume-title":"SF\u201036 Physical and Mental Health Summary Scales: A User\u2019s Manual","author":"Ware JE","year":"1994"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-006-9092-z"},{"key":"e_1_2_8_20_2","unstructured":"WareJrJE SnowK KowinskiM GandekB.SF\u201036 health survey: manual and interpretation guide.1993."},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.07.031"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780100410"},{"key":"e_1_2_8_23_2","first-page":"IV1","article-title":"Second European Consensus Document on chronic critical leg ischemia","volume":"84","author":"Dormandy J","year":"1991","journal-title":"Circulation"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.5.604"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000296010.21252.78"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-009-9561-4"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/14034948010290010601"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyr112"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(99)00102-6"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(02)00311-2"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.163"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2007.114041"}],"container-title":["Journal of Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2796.2012.02521.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2796.2012.02521.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T10:12:00Z","timestamp":1697364720000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2796.2012.02521.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2,26]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1111\/j.1365-2796.2012.02521.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2796.2012.02521.x","archive":["Portico"],"relation":{},"ISSN":["0954-6820","1365-2796"],"issn-type":[{"value":"0954-6820","type":"print"},{"value":"1365-2796","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,2,26]]}}}