{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:11:59Z","timestamp":1769631119069,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T00:00:00Z","timestamp":1315440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p><jats:bold>Summary\u2002<\/jats:bold> Hypophosphatemic rickets (HR) is a rare hereditary disease in which dental problems in terms of spontaneous periapical infections are frequently reported. Most previous reports have been based on a small number of HR patients and have been published before the disease could be confirmed genetically. The aim of the present study was to describe the periapical and endodontic status of permanent teeth in patients with genetically and\/or biochemically confirmed HR. The patients were recruited from a medical study on HR patients. The patients underwent a dental examination including a digital panoramic radiograph, which was scored for endodontically affected teeth (i.e. teeth with periapical radiolucencies and\/or endodontically treated teeth). A total of 52 patients (age range: 5\u00b77\u201374\u00b75\u2003years; 17 males and 35 females) were included. HR patients were characterised by a high number of endodontically affected teeth (mean: 4\u00b72; s.d.: 5\u00b70). The number of affected teeth rose significantly with age (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030\u00b701), and no statistically significant gender difference was found. The relative distribution of endodontically affected teeth in the three tooth groups (incisors and canines, premolars, and molars) varied according to age. In the youngest age group, only incisors and canines were affected, while the relative proportion of affected premolars and molars increased with age. Endodontically affected teeth are common in HR patients, and the number of affected teeth increased significantly with age. Hence, the need for endodontic treatment among HR patients is comprehensive.<\/jats:p>","DOI":"10.1111\/j.1365-2842.2011.02250.x","type":"journal-article","created":{"date-parts":[[2011,9,8]],"date-time":"2011-09-08T12:52:53Z","timestamp":1315486373000},"page":"144-150","source":"Crossref","is-referenced-by-count":35,"title":["Periapical and endodontic status of permanent teeth in patients with hypophosphatemic rickets"],"prefix":"10.1111","volume":"39","author":[{"given":"M. G.","family":"ANDERSEN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. S.","family":"BECK\u2010NIELSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"HAUBEK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"HINTZE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"GJ\u00d8RUP","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"POULSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9,8]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-08-0818"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng1095-130"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2003.tb00026.x"},{"key":"e_1_2_7_5_2","first-page":"69","article-title":"X\u2010linked hypophosphatemia: dental and histologic findings","volume":"72","author":"Batra P","year":"2006","journal-title":"J Canad Dent Assoc."},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2003.116"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2000.107522"},{"key":"e_1_2_7_8_2","first-page":"61","article-title":"Prevalence and pathogenesis of dental and periodontal lesions in children with X\u2010linked hypophosphatemic rickets","volume":"7","author":"Baroncelli GI","year":"2006","journal-title":"Eur J Paediatr Dent."},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00029330-200708020-00020"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4477.2001.tb00340.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-006-0182-4"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.119"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2006.01326.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2008.12.003"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1159\/000151382"},{"key":"e_1_2_7_16_2","first-page":"111","article-title":"Vitamin\u2010D\u2010resistant rickets: report of a case","volume":"104","author":"Page LA","year":"2008","journal-title":"N Z Dent J."},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200404000-00015"},{"key":"e_1_2_7_18_2","first-page":"199","article-title":"Hereditary hypophosphatemia","volume":"36","author":"Gardner DE","year":"1969","journal-title":"ASDC J Dent Child."},{"key":"e_1_2_7_19_2","first-page":"505","article-title":"The importance of the dental exam","volume":"44","author":"Harrell RM","year":"1983","journal-title":"N C Med J."},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1960.tb01937.x"},{"key":"e_1_2_7_21_2","first-page":"223","article-title":"Hereditary hypophosphatemia rickets: an important awareness for dentists","volume":"53","author":"Herbert FL","year":"1986","journal-title":"ASDC J Dent Child."},{"key":"e_1_2_7_22_2","first-page":"328","article-title":"Oral manifestations of familial hypophosphatemic rickets after phosphate supplement therapy: a review of the literature and report of case","volume":"58","author":"Larmas M","year":"1991","journal-title":"ASDC J Dent Child."},{"key":"e_1_2_7_23_2","first-page":"222","article-title":"Abnormal dentition in vitamin D resistant rickets. A case report","volume":"37","author":"Wihr NL","year":"1970","journal-title":"ASDC J Dent Child."},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-010-9373-0"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1986.tb00119.x"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2001.00370.x"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2006.01326.x"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(89)90110-6"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2842.2011.02250.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2842.2011.02250.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T17:23:48Z","timestamp":1698686628000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2842.2011.02250.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,8]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.1111\/j.1365-2842.2011.02250.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2842.2011.02250.x","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,8]]}}}