{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T06:50:54Z","timestamp":1794639054084,"version":"4.9.1"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,10,15]],"date-time":"2011-10-15T00:00:00Z","timestamp":1318636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:p><jats:bold>Summary\u2002<\/jats:bold> The aim of the present pilot investigation was to compare the effectiveness of six treatment protocols providing temporomandibular joint (TMJ) arthrocentesis with or without additional drugs to manage symptoms in patients with inflammatory\u2010degenerative TMJ disease. A consecutive series of 72 patients with TMJ osteoarthritis (axis group IIIb) with pain lasting from more than 6\u2003months were randomly assigned to one of the groups receiving the following treatment protocols: single\u2010session two\u2010needle arthrocentesis (A), single\u2010session two\u2010needle arthrocentesis plus corticosteroid (B), single\u2010session two\u2010needle arthrocentesis plus low molecular weight hyaluronic acid (HA) (C), single\u2010session two\u2010needle arthrocentesis plus high molecular weight HA (D), 5\u2003weekly two\u2010needle arthrocenteses plus low molecular weight HA (E) and 5\u2003weekly single\u2010needle arthrocenteses plus low molecular weight HA (F). At the 3\u2010month follow\u2010up, improvement with respect to mean baseline values was recorded in all the five treatment groups completing the protocol. No significant differences emerged between groups in any outcome variable. The protocol providing five sessions of two\u2010needle arthrocenteses plus low molecular weight HA allowed achieving the highest improvement in almost all the outcome variables. Findings suggested that no statistically significant differences existed between the treatment groups. The clinical significance of these findings needs to be tested with future studies on larger samples with longer follow\u2010up periods.<\/jats:p>","DOI":"10.1111\/j.1365-2842.2011.02265.x","type":"journal-article","created":{"date-parts":[[2011,10,15]],"date-time":"2011-10-15T06:42:10Z","timestamp":1318660930000},"page":"245-251","source":"Crossref","is-referenced-by-count":104,"title":["Arthrocentesis with or without additional drugs in temporomandibular joint inflammatory\u2010degenerative disease: comparison of six treatment protocols*"],"prefix":"10.1111","volume":"39","author":[{"given":"D.","family":"MANFREDINI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"RANCITELLI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"FERRONATO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"GUARDA\u2010NARDINI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,10,15]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"CD004973","article-title":"Arthrocentesis and lavage for treating temporomandibular joint disorders","volume":"4","author":"Guo C","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1179\/crn.2010.023"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(91)90409-F"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(97)90233-0"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000070570"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-002-0456-z"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2005.01505.x"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200535100-00003"},{"key":"e_1_2_7_10_2","first-page":"921","volume-title":"Conn\u2019s current therapy","author":"Ehrlich GE","year":"2006"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2006.12.021"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.03.715"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2007.01759.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2001.26716"},{"key":"e_1_2_7_15_2","first-page":"301","article-title":"Research diagnostic criteria for temporomandibular disorders: review, criteria examinations and specifications, critique","volume":"6","author":"Dworkin S","year":"1992","journal-title":"J Craniomandib Disord"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.08.031"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.12.006"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016358109162265"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(85)80050-1"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.08.024"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.01.067"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-8-200104170-00012"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1053\/joms.2001.23368"},{"key":"e_1_2_7_24_2","first-page":"305","volume-title":"Current concepts on temporomandibular disorders","author":"Manfredini D","year":"2010"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2842.2011.02265.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2842.2011.02265.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T16:30:04Z","timestamp":1697301004000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2842.2011.02265.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,15]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["10.1111\/j.1365-2842.2011.02265.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2842.2011.02265.x","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,15]]}}}