{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T06:45:56Z","timestamp":1698734756093},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T00:00:00Z","timestamp":1338854400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Oral Rehabilitation"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:p><jats:bold>Summary\u2002<\/jats:bold> Obstructive sleep apnoea (OSA) is one of the most common sleep disorders in elderly and represents a special problem for elderly patients. Elderly patients use a large number of drugs that might have an influence on the upper airway structure, anxiolytics or benzodiazepines being the most common. The aim of this study was to examine the effectiveness of mild or moderate OSA treatment with mandibular advance oral appliance in older lorazepam users compared with the age\u2010matched lorazepam\u2010free patients. A total of 40 functionally independent patients with the age of 65\u201374 were enrolled in the study. All included patients were found to suffer from at least two of the existing OSA symptoms (snoring, sleep fragmentation, daytime sleepiness) and were diagnosed with mild or moderate OSA after nocturnal polysomnography. Patients were divided into two groups. The experimental group consisted of 20 patients who used lorazepam in their daily therapy, and a control group consisted of 20 patients who did not take lorazepam. A mandibular advance appliance was made individually for each patient. Patients involved in the study were not overweight and were suggested to practise sleeping on the side and reduce alcohol consumption during the study. The study has shown that mandibular advance oral appliances were responsible for complete control of the OSA in over 37% of cases (15 patients). Patients have also reported substantial improvement in the symptoms; 80% of them reported that they had snored less, slept better (94%) and have not experienced daytime sleepiness (100%).<\/jats:p>","DOI":"10.1111\/j.1365-2842.2012.02324.x","type":"journal-article","created":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T16:40:41Z","timestamp":1338914441000},"page":"785-790","source":"Crossref","is-referenced-by-count":1,"title":["The effectiveness of oral appliances in elderly patients with obstructive sleep apnoea treated with lorazepam \u2013 a pilot study"],"prefix":"10.1111","volume":"39","author":[{"given":"L.","family":"TIHACEK\u2010SOJIC","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"ANDJELKOVIC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"MILIC\u2010LEMIC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"MILOSEVIC","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,5]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"The international classification of sleep disorders","author":"American Academy of Sleep Medicine","year":"2006"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.51.Suppl_2.S65"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.6.2004213"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200203-208OC"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/29.2.240"},{"key":"e_1_2_6_7_2","volume-title":"Stomatolo\u0161ka gerontoprotetika","author":"Tiha\u010dek\u2010\u0160oji\u0107 LJ","year":"2009"},{"key":"e_1_2_6_8_2","volume-title":"Principles of geriatric medicine and gerontology","author":"Hazzard WR","year":"1990"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199008233230805"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(00)00083-6"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043104"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200606000-00009"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198804000-00016"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-11-200606060-00004"},{"key":"e_1_2_6_15_2","volume-title":"Expert committee on physical status: the use and interpretation of anthropometric physical status","author":"World Health Organization","year":"1995"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"e_1_2_6_17_2","first-page":"236","article-title":"Treatment of obstructive sleep apnoea","volume":"131","author":"Veasey S","year":"2010","journal-title":"Indian J Med Res"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2008.01004.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.16.2013"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.45.4.353"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00148-008-0216-5"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2007.171"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.55.3.233"}],"container-title":["Journal of Oral Rehabilitation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2842.2012.02324.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2842.2012.02324.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T04:16:40Z","timestamp":1698639400000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2842.2012.02324.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,5]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1111\/j.1365-2842.2012.02324.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2842.2012.02324.x","archive":["Portico"],"relation":{},"ISSN":["0305-182X","1365-2842"],"issn-type":[{"value":"0305-182X","type":"print"},{"value":"1365-2842","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,5]]}}}