{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:15:31Z","timestamp":1763036131463},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,5,16]],"date-time":"2006-05-16T00:00:00Z","timestamp":1147737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Arousal from sleep can be a protective response to life\u2010threatening stimuli. Hence, faults within state\u2010switching processes may lead to fatal events. To investigate the role of the nervous system during cardiac failure triggered by phasic, vagally mediated stimulation, we analysed autonomic and behavioural reactions in 50 premature neonates during quiet sleep (QS) \u2013 a sleep state characterized by a preponderance of tonic, parasympathetic activity. Bradycardia was induced with a standardized ocular compression test. Neither awakening nor behavioural escape reactions were observed during or after an episode of bradycardia. Eighty\u2010six per cent of the provoked bradycardic episodes induced central apnoea. During QS, the neonates\u2019 respiratory response and arousability were found to be time\u2010dependent: when the test was performed early in the QS episode, apnoea was more frequent (94%), and no sleep state change occurred. When ocular compression was performed in the later part of the QS episode, a transition towards active sleep was observed, together with significantly fewer episodes of apnoea (64%). These results indicate that a progressive decrease in the respiratory system's responsiveness to phasic, parasympathetic stimulation occurs during QS, whereas arousability increases. Our study suggests that newborns could be more vulnerable to potentially fatal events during the initial portion of a QS episode.<\/jats:p>","DOI":"10.1111\/j.1365-2869.2006.00511.x","type":"journal-article","created":{"date-parts":[[2006,5,16]],"date-time":"2006-05-16T11:58:32Z","timestamp":1147780712000},"page":"167-173","source":"Crossref","is-referenced-by-count":8,"title":["Use of the oculocardiac reflex to assess vagal reactivity during quiet sleep in neonates"],"prefix":"10.1111","volume":"15","author":[{"given":"JACQUES","family":"DUCROCQ","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VIRGINIE","family":"CARDOT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PIERRE","family":"TOURNEUX","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KAREN","family":"CHARDON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FR\u00c9D\u00c9RIC","family":"TELLIEZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JEAN\u2010PIERRE","family":"LIBERT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALAIN","family":"DE BROCA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00c9RONIQUE","family":"BACH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,5,16]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"405","article-title":"Standardization of oculo\u2010cardiac reflex in infants under 3\u2003months of age","volume":"45","author":"De Broca A.","year":"1990","journal-title":"Pediatrie"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000241747"},{"key":"e_1_2_6_4_1","volume-title":"Manual of Methods for Recording and Analyzing Sleep\u2013Wakefulness States in Preterm and Full\u2010Term Infant","author":"Curzi\u2010Dascalova L.","year":"1996"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000014217"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0929-693X(96)86410-4"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2001.280.6.H2920"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.103.3.603"},{"key":"e_1_2_6_9_1","first-page":"55","volume-title":"Sleep and Cardiovascular Control","author":"Harper R. 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