{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T06:52:52Z","timestamp":1778914372648,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,9,23]],"date-time":"2008-09-23T00:00:00Z","timestamp":1222128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Sleepiness following 6\u2003h of sleep deprivation (SD) was evaluated with a rat multiple sleep latencies test (rMSLT), and the findings were compared to conventional polysomnographic measures of sleepiness. The 6\u2003h of SD was produced by automated activity wheels, and was terminated at either the end of the light period or at the beginning of the dark period. The rMSLT consisted of 5\u2003min wakefulness induced by sensory stimulation followed by 25\u2003min of freedom to sleep. This procedure was repeated every 30\u2003min for 3\u2003h and was designed to minimize the amount of sleep lost due to the testing procedure. In separate rats, 6\u2003h SD was followed by undisturbed recovery, allowing evaluation of conventional polysomnographic measures of sleepiness. Sleep onset latencies were reduced following SD, with recovery in the light (baseline\u2003=\u20038\u2003min, 3\u2003s versus post\u2010SD\u2003=\u20031\u2003min, 17\u2003s) and dark period (baseline\u2003=\u200314\u2003min, 17\u2003s versus 7\u2003min, 7\u2003s). Sleep onset latencies were not altered by varying the duration criterion for the first sleep bout (i.e., sleep bout length criteria of 10, 20, 30, or 60\u2003s were compared). Polysomnographic variables (non\u2010rapid eye movement sleep episode duration, delta power, and number of awakenings) also provided reliable indirect measures of sleepiness, regardless of whether the recovery sleep occurred in the light or dark period. Evaluation of effect size indicated that the rMSLT was a strong measure of sleepiness, and was influenced by homeostatic, circadian, and illumination factors. The rMSLT provided a simple, objective, robust and direct measure of sleepiness that was as effective as conventional polysomnographic measures of sleepiness.<\/jats:p>","DOI":"10.1111\/j.1365-2869.2008.00686.x","type":"journal-article","created":{"date-parts":[[2008,9,24]],"date-time":"2008-09-24T00:29:19Z","timestamp":1222216159000},"page":"365-375","source":"Crossref","is-referenced-by-count":18,"title":["Assessing sleepiness in the rat: a multiple sleep latencies test compared to polysomnographic measures of sleepiness"],"prefix":"10.1111","volume":"17","author":[{"given":"JAMES T.","family":"MCKENNA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOSHUA W.","family":"CORDEIRA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MICHAEL A.","family":"CHRISTIE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JAIME L.","family":"TARTAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOHN G.","family":"MCCOY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EUNHO","family":"LEE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROBERT W.","family":"MCCARLEY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ROBERT E.","family":"STRECKER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,11,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000262763.66023.be"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00370659"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(05)80062-2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2181-06.2006"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00663111"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(75)90209-7"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/074873048900400205"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2466\/pms.1979.48.2.495"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/9.4.519"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2006.10.008"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2006.05.010"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/001316447303300111"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.121.2.433"},{"key":"e_1_2_6_15_1","first-page":"198","article-title":"Sleep deprivation in rats: effects on EEG power spectra, vigilance states, and cortical temperature","volume":"261","author":"Franken P.","year":"1991","journal-title":"Am. 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