{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:00:05Z","timestamp":1790521205463,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,6,20]],"date-time":"2012-06-20T00:00:00Z","timestamp":1340150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Sleep Research"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>In the diagnostic work\u2010up of hypersomnias of central origin, the complaint of excessive daytime sleepiness should be objectively confirmed by MSLT findings. Indeed, the features and diagnostic utility of spontaneous daytime sleep at 24\u2003h continuous polysomnography (PSG) have never been investigated. We compared daytime PSG features to MSLT data in 98 consecutive patients presenting with excessive daytime sleepiness and with a final diagnosis of narcolepsy with cataplexy\/hypocretin deficiency (<jats:italic>n<\/jats:italic>\u2003=\u200339), narcolepsy without cataplexy (<jats:italic>n<\/jats:italic>\u2003=\u20037), idiopathic hypersomnia without long sleep time (<jats:italic>n<\/jats:italic>\u2003=\u200319), and \u2018hypersomnia\u2019 with normal sleep latency at MSLT (<jats:italic>n<\/jats:italic>\u2003=\u200333). Daytime sleep time was significantly higher in narcolepsy\u2010cataplexy but similar in the other groups. Receiver operating characteristics (ROC) curves showed that the number of naps during daytime PSG predicted a mean sleep latency \u22648\u2003min at MSLT with an area under the curve of 0.67\u2003\u00b1\u20030.05 (<jats:italic>P<\/jats:italic>\u2003=\u20030.005). The number of daytime sleep\u2010onset REM periods (SOREMPs) in spontaneous naps strikingly predicted the scheduled occurrence of two or more SOREMPs at MSLT, with an area under the ROC curve of 0.93\u2003\u00b1\u20030.03 (<jats:italic>P<\/jats:italic>\u2003&lt;\u200310<jats:sup>\u221212<\/jats:sup>). One spontaneous SOREMP during daytime had a sensitivity of 96% with specificity of 74%, whereas two SOREMPs had a sensitivity of 75%, with a specificity of 95% for a pathological REM sleep propensity at MSLT. The features of spontaneous daytime sleep well correlated with MSLT findings. Notably, the occurrence of multiple spontaneous SOREMPs during daytime clearly identified patients with narcolepsy, as well as during the MSLT.<\/jats:p>","DOI":"10.1111\/j.1365-2869.2012.01032.x","type":"journal-article","created":{"date-parts":[[2012,6,20]],"date-time":"2012-06-20T12:09:33Z","timestamp":1340194173000},"page":"32-40","source":"Crossref","is-referenced-by-count":108,"title":["Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin"],"prefix":"10.1111","volume":"22","author":[{"given":"FABIO","family":"PIZZA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KEIVAN K.","family":"MOGHADAM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STEFANO","family":"VANDI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STEFANIA","family":"DETTO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FRANCESCA","family":"POLI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EMMANUEL","family":"MIGNOT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RAFFAELE","family":"FERRI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GIUSEPPE","family":"PLAZZI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.2.393"},{"key":"e_1_2_7_3_1","volume-title":"ICSD\u20102\u2010 International Classification of Sleep Disorders: Diagnostic and Coding Manual","author":"American Academy of Sleep Medicine","year":"2005"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/30.10.1274"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.1.123"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.8.1423"},{"key":"e_1_2_7_7_1","first-page":"81","article-title":"[Clinico\u2010polygraphic considerations on essential \u2018slow sleep\u2019 narcolepsy]","volume":"19","author":"Berti Ceroni G.","year":"1967","journal-title":"Sist Nerv"},{"key":"e_1_2_7_8_1","first-page":"235","volume-title":"The Abnormalities of Sleep in Man, Proceedings of the XVth European Meeting on Electroencephalography, Bologna 1967","author":"Berti Ceroni G.","year":"1968"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2007.04.001"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2001.0168"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/sleep\/9.1.167","article-title":"Daytime sleep characteristics and their relationships with night sleep in the narcoleptic patient","volume":"9","author":"Billiard M.","year":"1986","journal-title":"Sleep"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1819.1998.tb00987.x"},{"key":"e_1_2_7_13_1","first-page":"557","article-title":"Sleep homeostasis and models of sleep regulation","volume":"14","author":"Borb\u00e9ly A. 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