{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:43:33Z","timestamp":1791265413349,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T00:00:00Z","timestamp":1305158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pharm &amp; Therapeutics"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:p>\n                    Jensen, V. F., Emborg, H.\u2010D., Aarestrup, F. M. Indications and patterns of therapeutic use of antimicrobial agents in the Danish pig production from 2002 to 2008.\n                    <jats:italic>J. vet. Pharmacol. Therap.<\/jats:italic>\n                    \u00a0\n                    <jats:bold>35<\/jats:bold>\n                    , 33\u201346.\n                  <\/jats:p>\n                  <jats:p>\n                    This study describes trends in the use and indications for prescriptions of antimicrobial agents in the Danish pig production in the period between 2002 and 2008 and is the first description of a complete prescription pattern for one animal species in an entire country. Data on all prescription for pigs in Denmark were retrieved from the VetStat database. Antimicrobial use was measured in defined animal daily doses (ADD) for the specific age\u2010group and in ADD\n                    <jats:sub>kg<\/jats:sub>\n                    as a measure of amounts used. According to the results of the ADD\n                    <jats:sub>kg<\/jats:sub>\n                    data, 26% of all antimicrobials were prescribed for sows, 38% for weaner pigs, and 33% for finisher pigs. In weaner and finisher pigs, gastrointestinal infections accounted for 74\u201383% and 56\u201365% of the use, while respiratory infections accounted for 9\u201317% and 18\u201324%, respectively. From 2002 to 2008, prescription for respiratory disease increased by 145% for sows\/piglets, by 141% for weaning pigs, and by 81% for finisher pig. The most commonly used class of antibiotics was tetracycline for all age\u2010groups, replacing the previously used macrolide\/lincosamide group. The use of pleuromutilin increased in 2008 to the level of macrolides. In sow\/piglets, the second most used class was penicillins. The switch in choice of antimicrobial classes prescribed seems to be related primarily to changes in the price of the drugs.\n                  <\/jats:p>","DOI":"10.1111\/j.1365-2885.2011.01291.x","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T08:27:21Z","timestamp":1305188841000},"page":"33-46","source":"Crossref","is-referenced-by-count":63,"title":["Indications and patterns of therapeutic use of antimicrobial agents in the Danish pig production from 2002 to 2008"],"prefix":"10.1111","volume":"35","author":[{"given":"V. F.","family":"JENSEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010D.","family":"EMBORG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. M.","family":"AARESTRUP","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7843.2005.pto960401.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1305.061489"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.6.5.733"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1466252308001503"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.71.7.726"},{"key":"e_1_2_6_7_1","unstructured":"Anonymous. (2003)First Joint FAO\/OIE\/WHO Expert Workshop on Non\u2010Human Antimicrobial Usage and Antimicrobial Resistance: Scientific Assessment. Geneva Switzerland 1\u20135 December 2003. Available athttp:\/\/www.who.int\/foodsafety\/publications\/micro\/en\/amr.pdf. Accessed 28 December 2009."},{"key":"e_1_2_6_8_1","unstructured":"Anonymous. (2004)Second Joint FAO\/OIE\/WHO Expert Workshop on Non Human Antimicrobial Usage and Antimicrobial Resistance: Management Options. Oslo Norway 15\u201318 March 2004. Available athttp:\/\/www.who.int\/foodborne_disease\/resistance\/fdb_antimicrobial_Mar04.pdf. Accessed 28 December 2009."},{"key":"e_1_2_6_9_1","unstructured":"Anonymous. (2008) Development in antibiotic consumption expenses and prices for prescription veterinary medicines for production animals from April 1 2005 to April1 2008. Report of December 15 2008 to the Danish Ministry of Health. The Danish Medicines Agency Danish Veterinary and Food Administration and Technological University of Denmark. Copenhagen 2008."},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2807\/esm.08.02.00399-en","article-title":"Investigation of human infections with Salmonella enterica serovar Java in Scotland and possible association with imported poultry","volume":"8","author":"Brown D.J.","year":"2003","journal-title":"Euro Surveillance"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/599374"},{"key":"e_1_2_6_12_1","unstructured":"DANMAP 2007. (2008)Use of antimicrobial agents and occurrence of anti\u2010microbial resistance in bacteria from food animals foods and humans in Denmark. Copenhagen. ISSN 1600\u20101032. (accessible onhttp:\/\/www.danmap.org)."},{"key":"e_1_2_6_13_1","unstructured":"DANMAP 2008. (2009)Use of antimicrobial agents and occurrence of anti\u2010microbial resistance in bacteria from food animals foods and humans in Denmark. Copenhagen. ISSN 1600\u20101032. (accessible onhttp:\/\/www.danmap.org)."},{"key":"e_1_2_6_14_1","unstructured":"DANMAP 2009. (2010)Use of antimicrobial agents and occurrence of anti\u2010microbial resistance in bacteria from food animals foods and humans in Denmark. Copenhagen. ISSN 1600\u20101032. (accessible onhttp:\/\/www.danmap.org)."},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2007.0002"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2004.04.001"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.105.20.468"},{"key":"e_1_2_6_18_1","unstructured":"Statistics Denmark. Available athttp:\/\/www.statistikbanken.dk\/statbank5a\/default.asp?w=1024. 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