{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T17:37:26Z","timestamp":1775151446596,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,2,14]],"date-time":"2005-02-14T00:00:00Z","timestamp":1108339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:p><jats:bold>Summary.\u2002<\/jats:bold> Studies on hepatitis C virus (HCV) monoinfected patients suggest high sustained treatment response rates of up to 98% when interferon monotherapy is administered during the acute phase of HCV\u2010infection. To clarify whether early treatment of acute hepatitis C is similarly efficient in human immunodeficiency virus (HIV) positive patients, we conducted a retrospective survey of HIV\u2010positive patients with acute HCV infection. Eleven HIV\u2010positive patients who had been treated with interferon or interferon\/ribavirin were identified at eight HIV\u2010specialty outpatient clinics. The patients had been treated over a median 25\u2003weeks with standard interferon (two patients), pegylated interferon (four patients) and pegylated interferon in combination with ribavirin (five patients). A post\u2010treatment response (negative serum HCV\u2010RNA at the end of treatment) was seen in 10 of 11 patients and HCV\u2010RNA remained undetectable 24\u2003weeks after the end of treatment in all the 10 responders. Alanine aminotransferase (ALT) normalized in eight patients while two virological responders and one nonresponder showed persistent mild ALT elevations. In conclusion, early treatment of acute hepatitis C seems to achieve high sustained virological treatment response rates also in patients with HIV\u2010infection.<\/jats:p>","DOI":"10.1111\/j.1365-2893.2005.00580.x","type":"journal-article","created":{"date-parts":[[2005,2,17]],"date-time":"2005-02-17T20:53:59Z","timestamp":1108673639000},"page":"207-211","source":"Crossref","is-referenced-by-count":47,"title":["Treatment of acute hepatitis C infection in HIV\u2010infected patients: a retrospective analysis of eleven cases"],"prefix":"10.1111","volume":"12","author":[{"given":"M.","family":"Vogel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Bieniek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Jessen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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