{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T04:19:46Z","timestamp":1776917986183,"version":"3.51.2"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T00:00:00Z","timestamp":1302134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Viral Hepatitis"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p><jats:bold>Summary.\u2002<\/jats:bold> Hepatitis A is a widespread infectious disease. The prevalence of the disease is closely related to socioeconomic status (SES) and environmental factors. Understanding its prevalence is essential for instituting appropriate precautions. The aim of this study was to determine the prevalence of hepatitis A and evaluate the associated demographic features in children and young adults in Istanbul. In total, 630 individuals between the ages of 5\u201324 were included in the study. They were classified into four age groups (5\u20139, 10\u201314, 15\u201319 and 20\u201324\u2003years). The seropositivity of hepatitis A in the whole study population was 40%. Age\u2010specific prevalence was 11.4% in children 5\u20139 years old, 29% in those 10\u201314\u2003years old, 49.7% in those 15\u201319\u2003years old and 69% in those 20\u201325\u2003years old. Seropositivity was associated with increasing age, low SES, large family size, low maternal educational level, use of unsafe drinking water and living in regions with poor infrastructure and incomplete urbanization. When we compared our results with previous seroprevalence studies performed in Istanbul, we found an epidemiological shift towards increasing age. Factors associated with changes in prevalence were urbanization and associated infrastructure improvement, knowledge of the disease by the population, use of good hygiene and use of vaccination in those at high risk.<\/jats:p>","DOI":"10.1111\/j.1365-2893.2011.01454.x","type":"journal-article","created":{"date-parts":[[2011,4,7]],"date-time":"2011-04-07T08:52:57Z","timestamp":1302166377000},"page":"72-76","source":"Crossref","is-referenced-by-count":20,"title":["Hepatitis a seroprevalence in children and young adults in Istanbul, Turkey: seroprevalence change and associated factors"],"prefix":"10.1111","volume":"19","author":[{"given":"N.","family":"Ceran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Y\u00fcksel Kocdogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Mert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130.","family":"Erdem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Dede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Adaleti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"\u00d6zy\u00fcrek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Karag\u00fcl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"G\u00f6kta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,4,7]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"1426","volume-title":"Principles and Practice of Infectious Disease","author":"Curry MP","year":"2005"},{"key":"e_1_2_6_3_2","first-page":"57","volume-title":"Viral Hepatit 2003","author":"Akbulut A","year":"2003"},{"key":"e_1_2_6_4_2","first-page":"288","volume-title":"Viral Hepatit 2003","author":"\u00c7ullu F","year":"2003"},{"key":"e_1_2_6_5_2","first-page":"52","volume-title":"Viral Hepatit 2007","author":"D\u00f6kmeta\u015f \u0130","year":"2007"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198510243131706"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(92)90544-T"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(92)90546-V"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(99)00467-3"},{"issue":"5","key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"628","DOI":"10.4269\/ajtmh.2002.66.628","article-title":"Age\u2010specific prevalence of antibodies to hepatitis A in Santiago, Chile; 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