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Several studies have shown that patients can successfully be treated for <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> in the context of methadone maintenance programmes, but little evidence exists evaluating <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> treatment models for substance users where methadone maintenance is not indicated. This retrospective cohort study involved 129 persons participating in psycho\u2010educational support groups and integrated, interprofessional, community\u2010based health services focused on the treatment for <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> among marginalized populations with high rates of crack cocaine use and mental health comorbidities. We sought to identify the factors associated with antiviral treatment uptake. Group participation improved access to health care. While 19% had previously seen an <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> specialist prior to group initiation, 59% saw an <jats:styled-content style=\"fixed-case\">HCV<\/jats:styled-content> specialist during the group. Half of the participants were nonimmune to hepatitis A or B at baseline, and 80% of these patients received immunization through the programme. The programme treated 24 patients with pegylated interferon and ribavirin and achieved a sustained virologic response (<jats:styled-content style=\"fixed-case\">SVR<\/jats:styled-content>) rate of 91% for genotype 2 or 3 and 54% for genotype 1. Stable housing was independently associated with initiation of treatment, and there was a nonsignificant trend towards lower rates of treatment initiation among women. <jats:styled-content style=\"fixed-case\">SVR<\/jats:styled-content> rates for those who had used crack or injection drugs in the month prior to joining the programme did not differ significantly from those who had abstained.<\/jats:p>","DOI":"10.1111\/j.1365-2893.2012.01648.x","type":"journal-article","created":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T05:27:11Z","timestamp":1343712431000},"page":"836-842","source":"Crossref","is-referenced-by-count":47,"title":["Factors associated with <scp>HCV<\/scp> antiviral treatment uptake among participants of a community\u2010based <scp>HCV<\/scp> programme for marginalized patients"],"prefix":"10.1111","volume":"19","author":[{"given":"A.","family":"Charlebois","sequence":"first","affiliation":[{"name":"Department of Family and Community Medicine University of Toronto Toronto ON Canada"},{"name":"St. Michael's Hospital Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine University of Toronto Toronto ON Canada"},{"name":"St. Michael's Hospital Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Cooper","sequence":"additional","affiliation":[{"name":"South Riverdale Community Health Centre Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Mason","sequence":"additional","affiliation":[{"name":"South Riverdale Community Health Centre Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Powis","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Toronto Toronto ON Canada"},{"name":"Toronto East General Hospital Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,7,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-10-200605160-00004"},{"key":"e_1_2_7_3_1","volume-title":"A Study to Characterize the Epidemiology of Hepatitis C Infection in Canada, 2002. 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