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GABA is transported into <jats:italic>A. tumefaciens<\/jats:italic> via an ABC transporter dependent on the periplasmic binding protein Atu2422. We demonstrate that expression of <jats:italic>atu2422<\/jats:italic> and two other ABC transporter genes is downregulated by the conserved small RNA (sRNA) AbcR1 (for ABC regulator). AbcR1 is encoded in tandem with another sRNA, which is similar in sequence and structure. Both sRNAs accumulate during stationary phase but only the absence of AbcR1 resulted in significant accumulation of Atu2422 and increased GABA import. AbcR1 inhibits initiation of <jats:italic>atu2422<\/jats:italic> translation by masking its Shine\u2013Dalgarno sequence and thereby reduces stability of the <jats:italic>atu2422<\/jats:italic> transcript. It is the first described bacterial sRNA that controls uptake of a plant\u2010generated signalling molecule. Given that similar sRNAs and ABC transporter genes are present in various <jats:italic>Rhizobiaceae<\/jats:italic> and in <jats:italic>Brucella<\/jats:italic>, it is likely that such sRNA\u2010mediated control impacts a number of host\u2013microbe interactions.<\/jats:p>","DOI":"10.1111\/j.1365-2958.2011.07589.x","type":"journal-article","created":{"date-parts":[[2011,2,15]],"date-time":"2011-02-15T07:12:41Z","timestamp":1297753961000},"page":"492-506","source":"Crossref","is-referenced-by-count":74,"title":["Small RNA\u2010mediated control of the <i>Agrobacterium tumefaciens<\/i> GABA binding protein"],"prefix":"10.1111","volume":"80","author":[{"given":"Ina","family":"Wilms","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Voss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang 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