{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:05:35Z","timestamp":1790726735706,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,3,26]],"date-time":"2008-03-26T00:00:00Z","timestamp":1206489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:p><jats:bold>Abstract\u2002<\/jats:bold> Impaired accommodation to a meal has been recognized as a pathophysiological mechanism in functional dyspepsia (FD). Based on observations in tertiary care patients, the drinking test has been proposed as a non\u2010invasive tool to estimate accommodation. Our aim was to assess the reproducibility of the drinking test and its correlation with demographic, symptomatic and pathophysiological parameters in secondary care FD patients and healthy controls. Thirty\u2010four healthy controls and 78 FD patients completed a drinking test (3 respectively 2 times), a gastric emptying study and an FD symptom questionnaire. Factors influencing maximal volume and gastric emptying were determined, and the reproducibility of the drinking test was investigated. The maximal satiety was reached at a lower volume in patients (489\u2003\u00b1\u2003276 and 503\u2003\u00b1\u2003248\u2003mL for first and second test respectively <jats:italic>vs<\/jats:italic> 937\u2003\u00b1\u2003428 and 1048\u2003\u00b1\u2003421\u2003mL, <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.0001). The ingested amount depended on age, sex and baseline FD symptom score. Patients\u2019 sex, final satiety score, total score for stomach complaints at screening and total symptom score before test accounted for the total symptom score after the test. The slow nutrient drinking test confirms its possible role as an attractive non\u2010invasive and reproducible tool for the diagnosis of impaired accommodation and for the assessment of treatment responsiveness.<\/jats:p>","DOI":"10.1111\/j.1365-2982.2008.01092.x","type":"journal-article","created":{"date-parts":[[2008,3,27]],"date-time":"2008-03-27T05:48:04Z","timestamp":1206596884000},"page":"320-329","source":"Crossref","is-referenced-by-count":45,"title":["Reproducibility and symptomatic predictors of a slow nutrient drinking test in health and in functional 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