{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:15:27Z","timestamp":1758122127870},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,12,12]],"date-time":"2011-12-12T00:00:00Z","timestamp":1323648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2012,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> While bowel and bladder dysfunction are recognized consequences of a radical hysterectomy, the effects of a simple hysterectomy on anorectal sensorimotor functions, particularly rectal sensation, vary among studies and the effects on rectal compliance remain unknown. Our aims were to prospectively evaluate anorectal sensorimotor functions before and after a hysterectomy.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Anal pressures, rectal compliance, capacity, sensation, and bowel symptoms were assessed before, at 2\u2003months, and at 1\u2003year after a simple vaginal hysterectomy for benign indications in 19 patients. Rectal staircase (0\u201344\u2003mmHg, 4\u2010mmHg steps), ramp (0\u2013200\u2003mL at 50, 200 and 600\u2003mL\u2003min<jats:sup>\u22121<\/jats:sup>) and phasic distentions (8, 16, and 24\u2003mmHg above operating pressure) were performed.<\/jats:p><jats:p><jats:bold>Key Results\u2002<\/jats:bold> Anal resting (63\u2003\u00b1\u20034 before, 56\u2003\u00b1\u20034\u2003mmHg after) and squeeze pressures (124\u2003\u00b1\u200312 before, 124\u2003\u00b1\u200312\u2003mmHg after), rectal compliance and capacity (285\u2003\u00b1\u200312 before, 290\u2003\u00b1\u200311\u2003mL 1\u2003year after), and perception of phasic distentions were not different before <jats:italic>vs<\/jats:italic> after a hysterectomy. Sensory thresholds for first sensation and the desire to defecate were also not different, but pressure and volume thresholds for urgency were somewhat greater (Hazard ratio\u2003=\u20030.7, 95% CI [0.5, 1.0]) 1\u2003year after (<jats:italic>vs<\/jats:italic> before) a hysterectomy. Rectal pressures were higher (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.0001) during fast compared with slow ramp distention; this rate effect was greater at 1\u2003year after a hysterectomy, particularly at 100\u2003mL (<jats:italic>P<\/jats:italic>\u2003=\u20030.04).<\/jats:p><jats:p><jats:bold>Conclusions &amp; Inferences\u2002<\/jats:bold> A simple vaginal hysterectomy has relatively modest effects (i.e., somewhat reduced rectal urgency and increased stiffness during rapid distention) on rectal sensorimotor functions.<\/jats:p>","DOI":"10.1111\/j.1365-2982.2011.01825.x","type":"journal-article","created":{"date-parts":[[2011,12,13]],"date-time":"2011-12-13T03:37:54Z","timestamp":1323747474000},"page":"235-241","source":"Crossref","is-referenced-by-count":5,"title":["Effects of vaginal hysterectomy on anorectal sensorimotor functions \u2013 a prospective study"],"prefix":"10.1111","volume":"24","author":[{"given":"A. 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