{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T21:40:57Z","timestamp":1773178857813,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T00:00:00Z","timestamp":1341532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogastroenterology Motil"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Inter\u2010observer variability limits the reproducibility of pelvic floor motion measured by magnetic resonance imaging (MRI). Our aim was to develop a semi\u2010automated program measuring pelvic floor motion in a reproducible and refined manner.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> Pelvic floor anatomy and motion during voluntary contraction (squeeze) and rectal evacuation were assessed by MRI in 64 women with fecal incontinence (FI) and 64 age\u2010matched controls. A radiologist measured anorectal angles and anorectal junction motion. A semi\u2010automated program did the same and also dissected anorectal motion into perpendicular vectors representing the puborectalis and other pelvic floor muscles, assessed the pubococcygeal angle, and evaluated pelvic rotation.<\/jats:p><jats:p><jats:bold>Key Results\u2002<\/jats:bold> Manual and semi\u2010automated measurements of anorectal junction motion (<jats:italic>r<\/jats:italic>\u2003=\u20030.70; <jats:italic>P<\/jats:italic>\u2003&lt;\u20030.0001) during squeeze and evacuation were correlated, as were anorectal angles at rest, squeeze, and evacuation; angle change during squeeze or evacuation was less so. Semi\u2010automated measurements of anorectal and pelvic bony motion were also reproducible within subjects. During squeeze, puborectalis injury was associated (<jats:italic>P<\/jats:italic>\u2003\u2264\u20030.01) with smaller puborectalis but not pelvic floor motion vectors, reflecting impaired puborectalis function. The pubococcygeal angle, reflecting posterior pelvic floor motion, was smaller during squeeze and larger during evacuation. However, pubococcygeal angles and pelvic rotation during squeeze and evacuation did not differ significantly between FI and controls.<\/jats:p><jats:p><jats:bold>Conclusion &amp; Inferences\u2002<\/jats:bold> This semi\u2010automated program provides a reproducible, efficient, and refined analysis of pelvic floor motion by MRI. Puborectalis injury is independently associated with impaired motion of puborectalis, not other pelvic floor muscles in controls and women with FI.<\/jats:p>","DOI":"10.1111\/j.1365-2982.2012.01962.x","type":"journal-article","created":{"date-parts":[[2012,7,6]],"date-time":"2012-07-06T06:37:30Z","timestamp":1341556650000},"source":"Crossref","is-referenced-by-count":22,"title":["Semi\u2010automated vectorial analysis of anorectal motion by magnetic resonance defecography in healthy subjects and fecal incontinence"],"prefix":"10.1111","volume":"24","author":[{"given":"J.","family":"Noelting","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"Bharucha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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