{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:54:41Z","timestamp":1791140081817,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,6,8]],"date-time":"2006-06-08T00:00:00Z","timestamp":1149724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Our objective was to investigate the association of childhood leukaemia with selected maternal and birth characteristics by conducting a population\u2010based case\u2013control study using linked cancer registry and birth certificate records for Washington State. We compared maternal and infant characteristics of 595 Washington\u2010born residents &lt;20\u2003years old with leukaemia diagnosed during 1981\u20132003, and 5950 control children, using stratified analysis and logistic regression. Maternal age 35+ years (odds ratio [OR] 1.5; 95% confidence interval [CI] 1.1, 2.0), infant birthweight 4000+\u2003g (OR 1.4; 95% CI 1.1, 1.8), neonatal jaundice (OR 1.5; 95% CI 1.1, 2.1), and Down\u2019s syndrome (OR 31.3; 95% CI 6.4, 153.4) were associated with an increased risk of leukaemia. Among women with 2+ pregnancies, having at least two prior early (&lt;20\u2003weeks\u2019 gestation) fetal deaths was also associated with an increased risk (OR 1.5; 95% CI 0.97, 2.1). Maternal unmarried status (OR 0.7; 95% CI 0.6, 0.9) and African American race (OR 0.5; 95% CI 0.3, 0.9) were associated with a decreased risk. These results were more marked for acute lymphocytic leukaemia (ALL) than for acute myeloid leukaemia (AML), and for leukaemia diagnosed &lt;5\u2003years of age. These results may provide clues to the aetiology of childhood leukaemia. Genetic epidemiological studies are needed to expand our knowledge of inherent and possibly prenatal influences on the occurrence of this disease.<\/jats:p>","DOI":"10.1111\/j.1365-3016.2006.00731.x","type":"journal-article","created":{"date-parts":[[2006,6,8]],"date-time":"2006-06-08T08:40:31Z","timestamp":1149756031000},"page":"312-322","source":"Crossref","is-referenced-by-count":86,"title":["Maternal and birth characteristics in relation to childhood leukaemia"],"prefix":"10.1111","volume":"20","author":[{"given":"Danise","family":"Podvin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie M.","family":"Kuehn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth 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