{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:20:07Z","timestamp":1790666407934,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,4,8]],"date-time":"2010-04-08T00:00:00Z","timestamp":1270684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Paediatric Perinatal Epid"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Basta NO, James PW, Craft AW, McNally RJQ. Season of birth and diagnosis for childhood cancer in Northern England, 1968\u20132005.\n                    <jats:italic>Paediatric and Perinatal Epidemiology<\/jats:italic>\n                    2010;\n                    <jats:bold>24<\/jats:bold>\n                    : 309\u2013318.\n                  <\/jats:p>\n                  <jats:p>The aim of this study was to investigate seasonal variation in the incidence of cancer in children aged 0\u201314 years. Details of 2959 primary malignant cases (1659 males, 1300 females), diagnosed during the period 1968\u20132005, were extracted from a specialist registry (the Northern Region Young Persons' Malignant Disease Registry). Seasonal variation was analysed with respect to month of birth and diagnosis. The chi\u2010squared heterogeneity test was used to test for non\u2010uniform variation. Poisson regression analysis was used to fit sinusoidal (harmonic) models to the data, using month of birth and month of diagnosis, respectively, as covariates in separate models.<\/jats:p>\n                  <jats:p>\n                    There was significant sinusoidal variation based on month of birth for acute lymphoblastic leukaemia (ALL) aged 1\u20136 years (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.04; peak in March). For 0\u2010 to 14\u2010year\u2010old boys, there was statistically significant sinusoidal variation in month of birth for acute non\u2010lymphocytic leukaemia (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.04; peak in September) and astrocytoma (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.03; peak in October). Based on month of diagnosis, there was statistically significant sinusoidal variation in girls for all lymphomas (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.048; peak in March) and Hodgkin lymphoma (HL) (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.005; peak in January), and in boys for osteosarcoma (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.049; peak in October). This study confirms previous findings of seasonal variation around the month of birth for childhood ALL (at the peak ages) and provides further evidence of seasonal variation around month of birth for astrocytoma and around month of diagnosis for HL. The results are consistent with a role for environmental factors in the aetiology of these diagnostic groups. Further studies are needed to examine putative candidate agents.\n                  <\/jats:p>","DOI":"10.1111\/j.1365-3016.2010.01112.x","type":"journal-article","created":{"date-parts":[[2010,4,8]],"date-time":"2010-04-08T10:39:14Z","timestamp":1270723154000},"page":"309-318","source":"Crossref","is-referenced-by-count":36,"title":["Season of birth and diagnosis for childhood cancer in Northern England, 1968\u20132005"],"prefix":"10.1111","volume":"24","author":[{"given":"Nermine O.","family":"Basta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan W.","family":"Craft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J. 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