{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T21:08:07Z","timestamp":1794085687521,"version":"4.8.0"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,3,3]],"date-time":"2006-03-03T00:00:00Z","timestamp":1141344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite Immunology"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Taenia solium <jats:italic>is a cestode parasite that causes cysticercosis in humans and pigs. This study examined the antibody responses in pigs immunized with the TSOL18 and TSOL45\u20101A recombinant vaccines against<\/jats:italic> T.\u00a0solium <jats:italic>cysticercosis. Immunization with these proteins induced specific, complement\u2010fixing antibodies against the recombinant antigens that are believed to be associated with vaccine\u2010induced protection against<\/jats:italic> T.\u00a0solium <jats:italic>infection. Sera from immunized pigs were used to define the linear B\u2010cell epitopes of TSOL18 and TSOL45\u20101A. Prominent reactivity was revealed to one linear epitope on TSOL18 and two linear epitopes on TSOL45\u20101A. These, and oncosphere antigens from other taeniid cestodes, contain a protein sequence motif suggesting that they may show a tertiary structure similar to the fibronectin type III domain (FnIII). Comparison of the location of linear antigenic epitopes in TSOL18 and TSOL45\u20101A within the proposed FnIII structure to those within related cestode vaccine antigens reveals conservation in the positioning of the epitopes between oncosphere antigens from different taeniid species.<\/jats:italic><\/jats:p>","DOI":"10.1111\/j.1365-3024.2006.00820.x","type":"journal-article","created":{"date-parts":[[2006,3,3]],"date-time":"2006-03-03T14:29:19Z","timestamp":1141396159000},"page":"191-199","source":"Crossref","is-referenced-by-count":23,"title":["Antibody responses and epitope specificities to the <i>Taenia solium<\/i> cysticercosis vaccines TSOL18 and TSOL45\u20101A"],"prefix":"10.1111","volume":"28","author":[{"given":"C. T.","family":"KYNGDON","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. G.","family":"GAUCI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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