{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T06:44:26Z","timestamp":1777963466057,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,12,14]],"date-time":"2011-12-14T00:00:00Z","timestamp":1323820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite Immunology"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Although immunity to Echinococcus granulosus in sheep has been shown to be antibody\u2010mediated and complement\u2010dependent and can be passively transferred in colostrum, in animals vaccinated with EG95, the relationship between protection against an oral challenge infection with E.\u00a0granulosus eggs and anti\u2010EG95 IgG ELISA absorbance values at the time of challenge has not been satisfactorily proven. Using a combination of results from three EG95 vaccination trials, we have found that the IgG ELISA absorbance at the time of challenge infection explains approximately 50% (<jats:italic>P<\/jats:italic>\u2003\u2264\u20030\u00b7001) of the variability in the percentage protection against an oral challenge with E.\u00a0granulosus eggs (transformed with arcsin).<\/jats:p>","DOI":"10.1111\/j.1365-3024.2011.01341.x","type":"journal-article","created":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T13:50:35Z","timestamp":1320155435000},"page":"40-44","source":"Crossref","is-referenced-by-count":24,"title":["Serological monitoring of protection of sheep against <i>Echinococcus granulosus<\/i> induced by the EG95 vaccine"],"prefix":"10.1111","volume":"34","author":[{"given":"D. D.","family":"HEATH","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"KOOLAARD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.1996.d01-114.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1996.tb01029.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004360050116"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10295-005-0046-3"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(02)00219-X"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.4.1.103"},{"key":"e_1_2_5_8_2","first-page":"209","article-title":"Vaccination on Hydatidology \u2013 State of the Art","volume":"32","author":"Heath DD","year":"1997","journal-title":"Arch Int Hidatid"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(99)00003-X"},{"key":"e_1_2_5_10_2","first-page":"27","article-title":"Immunity and vaccine control of Echinococcus granulosus infection in animal intermediate hosts","volume":"46","author":"Lightowlers MW","year":"2004","journal-title":"Parassitologia"},{"key":"e_1_2_5_11_2","first-page":"252","article-title":"The prophylactic effect of the genetically engineered vaccine EG95 on hydatid disease of sheep","volume":"24","author":"Zhang ZZ","year":"2008","journal-title":"Chin J Zoon"},{"key":"e_1_2_5_12_2","first-page":"85","article-title":"Development of monoclonal antibodies suitable for use in antigen quantification potency tests for clostridial veterinary vaccines","volume":"101","author":"Hauer P","year":"1999","journal-title":"Dev Biol Stand"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.65.685"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2004.11.003"},{"key":"e_1_2_5_15_2","first-page":"1223","article-title":"Comparison between Two In Vitro ELISA\u2010Based Assays in the Determination of Antivenom Potency","volume":"5","author":"Ibrahim N","year":"2009","journal-title":"J Appl Sci Res"},{"key":"e_1_2_5_16_2","volume-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook F","year":"1989"},{"key":"e_1_2_5_17_2","volume-title":"Current Protocols in Molecular Biology","author":"Ausubel FM","year":"1995"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.14.4121-4130.1995"},{"key":"e_1_2_5_19_2","volume-title":"GenStat for Windows Introduction","author":"Payne RW","year":"2010"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(94)90156-2"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(92)90144-A"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.10.6679"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-4758(99)01633-6"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.1998.00176.x"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.11.096"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(81)90035-7"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(92)90063-Q"}],"container-title":["Parasite Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-3024.2011.01341.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-3024.2011.01341.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T09:39:03Z","timestamp":1697276343000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-3024.2011.01341.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,14]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1111\/j.1365-3024.2011.01341.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-3024.2011.01341.x","archive":["Portico"],"relation":{},"ISSN":["0141-9838","1365-3024"],"issn-type":[{"value":"0141-9838","type":"print"},{"value":"1365-3024","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,14]]}}}