{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:17:26Z","timestamp":1793798246902,"version":"4.6.1"},"reference-count":70,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,10,12]],"date-time":"2011-10-12T00:00:00Z","timestamp":1318377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plant Cell &amp; Environment"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>In the present study, the significance of sulfite oxidase (SO) for sulfite detoxification and sulfur assimilation was investigated. In response to sulfur dioxide (SO<jats:sub>2<\/jats:sub>) exposure, a remarkable expansion of sulfate and a significant increase of GSH pool were observed in wild\u2010type and SO\u2010overexpressing <jats:italic>Arabidopsis<\/jats:italic>. These metabolic changes were connected with a negative feedback inhibition of adenosine 5\u2032\u2010phosphosulfate reductase (APR), but no alterations in gas exchange parameters or visible symptoms of injury. However, <jats:italic>Arabidopsis<\/jats:italic> SO\u2010KO mutants were consistently negatively affected upon 600\u2003nL\u2003L<jats:sup>\u22121<\/jats:sup> SO<jats:sub>2<\/jats:sub> exposure for 60\u2003h and showed phenotypical symptoms of injury with small necrotic spots on the leaves. The mean <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/PCE_2420_mu1.gif\" xlink:title=\"inline image\"\/> was reduced by about 60% over the fumigation period, accompanied by a reduction of net CO<jats:sub>2<\/jats:sub> assimilation and SO<jats:sub>2<\/jats:sub> uptake of about 50 and 35%. Moreover, sulfur metabolism was completely distorted. Whereas sulfate pool was kept constant, thiol\u2010levels strongly increased. This demonstrates that SO should be the only protagonist for back\u2010oxidizing and detoxification of sulfite. Based on these results, it is suggested that co\u2010regulation of SO and APR controls sulfate assimilation pathway and stabilizes sulfite distribution into organic sulfur compounds. In conclusion, a sulfate\u2013sulfite cycle driven by APR and SO can be postulated for fine\u2010tuning of sulfur distribution that is additionally used for sulfite detoxification, when plants are exposed to atmospheric SO<jats:sub>2<\/jats:sub>.<\/jats:p>","DOI":"10.1111\/j.1365-3040.2011.02420.x","type":"journal-article","created":{"date-parts":[[2011,9,6]],"date-time":"2011-09-06T14:09:41Z","timestamp":1315318181000},"page":"100-115","source":"Crossref","is-referenced-by-count":66,"title":["Sulfite oxidase controls sulfur metabolism under SO<sub>2<\/sub> exposure in <i>Arabidopsis thaliana<\/i>"],"prefix":"10.1111","volume":"35","author":[{"given":"D\u00d6RTE","family":"RANDEWIG","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DOMENICA","family":"HAMISCH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CORNELIA","family":"HERSCHBACH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MONIKA","family":"EIBLMEIER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHRISTIAN","family":"GEHL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JENS","family":"JURGELEIT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JESSICA","family":"SKERRA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RALF R.","family":"MENDEL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HEINZ","family":"RENNENBERG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROBERT","family":"H\u00c4NSCH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,10,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/38.1.99"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00345250"},{"key":"e_1_2_6_4_1","first-page":"1227","article-title":"Oxidative stress and antioxidative system in plants","volume":"82","author":"Arora A.","year":"2002","journal-title":"Current Science"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.1981.tb01718.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/45.7.879"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/46.1.73"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/284399a0"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111632200"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/12.22.8711"},{"key":"e_1_2_6_11_1","first-page":"96","volume-title":"Sulfur Dioxide and Vegetation. 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