{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:59:07Z","timestamp":1791874747702,"version":"4.3.4"},"reference-count":58,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,9,11]],"date-time":"2007-09-11T00:00:00Z","timestamp":1189468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scand J Immunol"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cytotoxic T lymphocytes recently stimulated by antigen\u2010presenting cells (APC) display major histocompatibility class (MHC) I and II molecules inherited from APC. We have previously reported that, <jats:italic>in vitro<\/jats:italic>, transfer of MHC molecules and several other proteins occurs through trogocytosis, i.e. the active acquisition of target cell membrane fragments by T lymphocytes. Here, using the model of viral antigen LCMVgp33\u201041 recognition in transgenic P14 mice, we show that CD8<jats:sup>+<\/jats:sup> T cells perform trogocytosis <jats:italic>in vivo<\/jats:italic>, as detected by the capture of biotin\u2010 or fluorescence\u2010labeled components of the APC surface. Trogocytosis occurs during interactions of CD8<jats:sup>+<\/jats:sup> T cells with at least two kinds of cells: target cells and dendritic cells (DC). In lymph nodes, CD8<jats:sup>+<\/jats:sup> T cells having performed trogocytosis with DC express the CD69 activation marker indicating that trogocytosis detects recently activated cells. Taken together, our findings suggest that trogocytosis may be a new <jats:italic>in vivo<\/jats:italic> marker of the recent interaction between a CD8<jats:sup>+<\/jats:sup> T cell and its cellular partners or targets.<\/jats:p>","DOI":"10.1111\/j.1365-3083.2007.01996.x","type":"journal-article","created":{"date-parts":[[2007,9,16]],"date-time":"2007-09-16T05:12:40Z","timestamp":1189919560000},"page":"441-450","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Capture of membrane components via trogocytosis occurs <i>in vivo<\/i> during both dendritic cells and target cells encounter by CD8<sup>+<\/sup> T cells"],"prefix":"10.1111","volume":"66","author":[{"given":"J.","family":"Riond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Elhmouzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Hudrisier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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