{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T18:23:26Z","timestamp":1790965406955,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,9,12]],"date-time":"2011-09-12T00:00:00Z","timestamp":1315785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scand J Immunol"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Sj\u00f6gren\u2019s syndrome (SS) is an autoimmune disease targeting the exocrine glands resulting in xerostomia\/keratoconjunctivitis sicca. Presently, we examined the levels and clinical correlations of IL\u201022 in SS. Patients with SS together with normal controls were randomly selected. IL\u201022 was detected at significantly higher levels in sera of patients with SS. The levels of IL\u201022 present in sera showed statistically significant direct correlations with hyposalivation, anti\u2010SSB, anti\u2010SSA\/SSB combined, hypergammaglobulinemia and rheumatoid factor. IL\u201022 showed a direct correlation with major clinical parameters. The data suggest that IL\u201022 plays a critical role in the development of SS, and further study is needed to examine its function in human SS.<\/jats:p>","DOI":"10.1111\/j.1365-3083.2011.02583.x","type":"journal-article","created":{"date-parts":[[2011,6,6]],"date-time":"2011-06-06T14:44:40Z","timestamp":1307371480000},"page":"377-382","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Expression of Interleukin\u201022 in Sj\u00f6gren\u2019s Syndrome: Significant Correlation with Disease Parameters"],"prefix":"10.1111","volume":"74","author":[{"given":"T. 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