{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T14:31:33Z","timestamp":1784817093483,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,3,16]],"date-time":"2012-03-16T00:00:00Z","timestamp":1331856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scand J Immunol"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The reports on fish parasite <jats:italic>Anisakis simplex<\/jats:italic> allergy have increased in countries with high fish consumption in the last decade. In Norway, a high consumption country, the prevalence of immunoglobulin E (IgE) sensitization to <jats:italic>A.\u00a0simplex<\/jats:italic> was still unknown. Thus, our objective was to investigate the sensitization prevalence in this country. At the Haukeland University Hospital, Bergen, Norway, two main groups of surplus serum samples were collected: one from newly recruited blood donors (BDO) and the other from the Allergy laboratory (ALL) after analysing IgE and IgE antibodies. The latter was divided into three series: one containing unsorted sera and two sorted by either Phadiatop<jats:sup>\u00ae<\/jats:sup>\u22650.35\u2003kU<jats:sub>A<\/jats:sub>\/l or total IgE \u22651000\u2003kU\/l. The sera were analysed for total IgE and IgE antibodies against <jats:italic>A.\u00a0simplex<\/jats:italic>, shrimp, house dust mite (HDM), cod and cross\u2010reactive carbohydrates (CCDs). The prevalence of IgE sensitization to <jats:italic>A.\u00a0simplex<\/jats:italic> was 2.0%, 2.2% and 6.6% in BDO, the unsorted and Phadiatop<jats:sup>\u00ae<\/jats:sup> positive serum groups, respectively. A considerable degree of cross\u2010sensitization to shrimp and HDM is further suggested. Unspecific binding because of high total IgE or by binding to CCDs seemed to play a minor role. The prevalence of IgE sensitization to <jats:italic>A.\u00a0simplex<\/jats:italic> appears to be lower in a Norwegian population than in other high fish\u2010consuming countries, but might still be overestimated owing to cross\u2010sensitization.<\/jats:p>","DOI":"10.1111\/j.1365-3083.2012.02670.x","type":"journal-article","created":{"date-parts":[[2012,3,16]],"date-time":"2012-03-16T06:45:57Z","timestamp":1331880357000},"page":"431-435","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["IgE Sensitization to the Fish Parasite <i>Anisakis simplex<\/i> in a Norwegian Population: A Pilot Study"],"prefix":"10.1111","volume":"75","author":[{"given":"A. 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