{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:49:53Z","timestamp":1791121793546,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,3,30]],"date-time":"2006-03-30T00:00:00Z","timestamp":1143676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:p><jats:bold><jats:sc>summary<\/jats:sc>.\u2002<\/jats:bold> Indigenous hepatitis E is increasingly recognized in developed countries, where it may be a zoonosis. We describe the first case of transfusion\u2010transmitted hepatitis E in the UK from a blood donor who had no history of recent travel abroad.<\/jats:p><jats:p>Follow\u2010up of the donor and recipients of the blood products was carried out using serological and molecular techniques.<\/jats:p><jats:p>Acute hepatitis E was transmitted to one of two recipients. The infected patient would have received a larger volume of the donor's plasma. HEV subgenomic sequences carried by the donor and recipient were identical.<\/jats:p><jats:p>This is the first case of post\u2010transfusion hepatitis E in the UK. Secondary transmission of hepatitis E indigenous to a nonhyperendemic country may occur by blood transfusion. It is important that blood donors inform the transfusion service of all post\u2010donation illnesses so that appropriate interventions can take place.<\/jats:p>","DOI":"10.1111\/j.1365-3148.2006.00652.x","type":"journal-article","created":{"date-parts":[[2006,3,30]],"date-time":"2006-03-30T09:35:36Z","timestamp":1143711336000},"page":"79-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":251,"title":["Transfusion\u2010transmitted hepatitis E in a \u2018nonhyperendemic\u2019 country"],"prefix":"10.1111","volume":"16","author":[{"given":"E.","family":"Boxall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Herborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Kochethu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ijaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.\u2010G.","family":"Teo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,3,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1005.030908"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20255"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20125"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.3.918-923.2001"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.1999.tb00031.x"},{"key":"e_1_2_5_7_1","unstructured":"Health Protection Agency (HPA) archive.[Available athttp:\/\/www.hpa.org.uk\/cdr\/archives]."},{"issue":"12","key":"e_1_2_5_8_1","doi-asserted-by":"crossref","first-page":"3828","DOI":"10.1128\/JCM.37.12.3828-3834.1999","article-title":"Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic Group with Taiwan isolates of human hepatitis E virus","volume":"37","author":"Hsieh S.Y.","year":"1999","journal-title":"Journal of Clinical Microbiology"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/444396"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2004.03437.x"},{"issue":"2","key":"e_1_2_5_11_1","first-page":"166","article-title":"Global epidemiology and medical aspects of hepatitis E","volume":"11","author":"Krawczynski K.","year":"2001","journal-title":"Forum (Genova)"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0958-7578.2005.00563.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20206"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2004.03300.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.18.9860"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.20215"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9071(199903)57:3<243::AID-JMV6>3.0.CO;2-R"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1086\/313430"},{"key":"e_1_2_5_19_1","unstructured":"Serious Hazards of Transfusion; Annual report(2003). 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