{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:56:17Z","timestamp":1774122977818,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T00:00:00Z","timestamp":1289347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion Medicine"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:p> <jats:bold>Objectives:<\/jats:bold> To determine if the age of packed red blood cells (PRBCs) is associated with adverse events or outcomes in patients with subarachnoid haemorrhage (SAH).<\/jats:p><jats:p> <jats:bold>Aim:<\/jats:bold> Analyse data on PRBC age to complications and outcomes in patients with SAH.<\/jats:p><jats:p> <jats:bold>Background:<\/jats:bold> Patients who receive a PRBC transfusion after SAH have a higher rate of complications, and older PRBC age may be responsible for this.<\/jats:p><jats:p> <jats:bold>Methods\/Materials:<\/jats:bold> We prospectively recorded clinical and demographic data, acute adverse effects related to transfusion, major hospital events, radiographic cerebral infarction, PRBC age and outcomes in 119 patients with SAH who received a PRBC transfusion. Patients were followed for outcomes at 14 days or discharge, 28 days and 3 months with the modified Rankin scale (a measure of neurologic function).<\/jats:p><jats:p> <jats:bold>Results:<\/jats:bold> In 241 PRBC transfusions, there was new fever in 36 (15%), hypotension in 23 (10%), pulmonary oedema or symptomatic respiratory distress in 5 (2%) and rash in 1 (1%). Age of PRBCs administered was not associated with vasospasm, cerebral infarction, acute adverse events or outcomes (<jats:italic>P<\/jats:italic> &gt; 0\u00b71 for all).<\/jats:p><jats:p> <jats:bold>Conclusions:<\/jats:bold> In this small registry of patients with SAH, the age of transfused PRBCs was not associated with adverse events or outcomes.<\/jats:p>","DOI":"10.1111\/j.1365-3148.2010.01048.x","type":"journal-article","created":{"date-parts":[[2010,11,10]],"date-time":"2010-11-10T08:43:19Z","timestamp":1289378599000},"page":"130-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Packed red blood cell age does not impact adverse events or outcomes after subarachnoid haemorrhage"],"prefix":"10.1111","volume":"21","author":[{"given":"A. M.","family":"Naidech","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"Liebling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. M.","family":"Duran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. L.","family":"Ault","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,11,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000258355.23810.c6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.556159"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199902113400601"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181692dfc"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1001\/jama.1993.03500230106037","article-title":"Effect of stored\u2010blood transfusion on oxygen delivery in patients with sepsis.","volume":"269","author":"Marik P.E.","year":"1993","journal-title":"The Journal of the American Medical Association"},{"key":"e_1_2_6_7_1","unstructured":"Naidech A.M. Shaibani A. Garg R.K.et al. (2010)Prospective randomized trial of higher goal hemoglobin after subarachnoid hemorrhage.Neurocritical Care DOI: 10.1007\/s12028\u2010010\u20109424\u20104 [Epub ahead of print]."},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181b39f1b"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31816a10a3"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-003-1665-7"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200205000-00018"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000162685.60609.49"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200605000-00005"}],"container-title":["Transfusion Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-3148.2010.01048.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-3148.2010.01048.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T16:07:13Z","timestamp":1697299633000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-3148.2010.01048.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,10]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1111\/j.1365-3148.2010.01048.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-3148.2010.01048.x","archive":["Portico"],"relation":{},"ISSN":["0958-7578","1365-3148"],"issn-type":[{"value":"0958-7578","type":"print"},{"value":"1365-3148","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,10]]},"assertion":[{"value":"2010-11-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}