{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T11:45:39Z","timestamp":1793879139751,"version":"4.7.0"},"reference-count":55,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives\u2003<\/jats:bold> To define the relative incidence of organisms causing blood stream infections in a tropical setting with a very low prevalence of human immunodeficiency virus infection (&lt;1%).<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> A 12\u2010month prospective study of blood stream infections in 2000 at Royal Darwin Hospital in the tropical north of Australia.<\/jats:p><jats:p><jats:bold>Results\u2003<\/jats:bold> Significant isolates were grown from 257 sets of blood cultures. <jats:italic>Staphylococcus aureus<\/jats:italic> was the most common isolate overall (28%); 26% of these were methicillin\u2010resistant (MRSA). <jats:italic>Escherichia coli<\/jats:italic> was the most common cause of community\u2010acquired bacteraemia. <jats:italic>Burkholderia pseudomallei<\/jats:italic> caused 32% of community acquired, bacteraemic pneumonia; 6% of bacteraemias overall. Vancomycin\u2010resistant enterococci were not isolated. Crude mortality rates (13% overall; 9% attributable mortality) were lower than in most comparable studies.<\/jats:p><jats:p><jats:bold>Conclusions\u2003<\/jats:bold> The major difference between these findings and surveys performed elsewhere is the presence of <jats:italic>B. pseudomallei<\/jats:italic> as a significant cause of bacteraemic community\u2010acquired pneumonia. Our results demonstrate the effects of local environmental and patient characteristics on the range of organisms causing blood stream infections, and emphasize the important role of local microbiology laboratories in guiding empiric antibiotic therapy.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2004.01269.x","type":"journal-article","created":{"date-parts":[[2004,7,2]],"date-time":"2004-07-02T06:28:48Z","timestamp":1088749728000},"page":"795-804","source":"Crossref","is-referenced-by-count":60,"title":["Epidemiology of community\u2010acquired and nosocomial bloodstream infections in tropical Australia: a 12\u2010month prospective study"],"prefix":"10.1111","volume":"9","author":[{"given":"Mark W.","family":"Douglas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Lum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhumur","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale A.","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas M.","family":"Anstey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart J.","family":"Currie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,7]]},"reference":[{"key":"e_1_2_25_2_1","first-page":"407","article-title":"Bacterial isolates involved in cases of septicaemia in a Nigerian hospital","volume":"67","author":"Ako\u2010Nai AK","year":"1990","journal-title":"East African Medical Journal"},{"key":"e_1_2_25_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/inf.1977.9.issue-3.05"},{"key":"e_1_2_25_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.1.83"},{"key":"e_1_2_25_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.2.685-686.2002"},{"key":"e_1_2_25_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(05)70354-8"},{"key":"e_1_2_25_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0702.010232"},{"key":"e_1_2_25_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/516297"},{"key":"e_1_2_25_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/314836"},{"key":"e_1_2_25_10_1","doi-asserted-by":"crossref","first-page":"86S","DOI":"10.1016\/0002-9343(91)90349-3","article-title":"Secular trends in nosocomial primary bloodstream infections in the United States, 1980\u20131989. 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