{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T07:17:21Z","timestamp":1793863041504,"version":"4.6.1"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,4,25]],"date-time":"2006-04-25T00:00:00Z","timestamp":1145923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Objective\u2002<\/jats:bold> To estimate the seroprevalence of human leptospirosis in southern Vietnam.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> All pupils (<jats:italic>n<\/jats:italic>\u2003=\u2003961) of two primary schools in two communes in southern Vietnam were screened for the presence of serum <jats:italic>Leptospira<\/jats:italic> immunoglobulin (Ig)G. <jats:italic>Leptospira<\/jats:italic> IgM was tested in 92 randomly selected samples. IgM and IgG were tested with a commercially available enzyme\u2010linked immunosorbent assay (ELISA).<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold>  <jats:italic>Leptospira<\/jats:italic> IgG was found in 123 (12.8%, 95% CI: 10.8\u201315.1) children with a male:female ratio of 1.5:1. At the age of 7\u2003years the prevalence was 11%. Log\u2010linear binary regression of the IgG seroprevalence by age showed a mean seroconversion rate of 1.5% (95% CI: 1.23\u20131.75) per year. Five (5.4%, 95% CI: 2.3\u201312.1) samples were definitely positive for IgM. Presence of serum <jats:italic>Leptospira<\/jats:italic> IgG antibodies was significantly associated with swimming in rivers (RR: 1.745, 95% CI: 1.117\u20132.724) and wading through water (RR 1.793, 95% CI: 1.181\u20132.722).<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Our data emphasize the importance of leptospirosis among children in Vietnam, despite the absence of severe disease, and stress the need for adequate and cheap diagnostics.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2006.01619.x","type":"journal-article","created":{"date-parts":[[2006,4,25]],"date-time":"2006-04-25T17:08:31Z","timestamp":1145984911000},"page":"738-745","source":"Crossref","is-referenced-by-count":34,"title":["Seroepidemiology of leptospirosis in southern Vietnamese children"],"prefix":"10.1111","volume":"11","author":[{"given":"Khoa T. 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