{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T15:11:19Z","timestamp":1791040279493,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2006,10,20]],"date-time":"2006-10-20T00:00:00Z","timestamp":1161302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tropical Med Int Health"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p> <jats:italic>Oesophagostomum bifurcum<\/jats:italic> is a common parasite of humans causing disease in parts of northern Ghana and northern Togo. The impact of repeated mass treatment with albendazole on infection with <jats:italic>O. bifurcum<\/jats:italic> and hookworm is analysed and the results compared with those in a control area where no treatment was given. At baseline, <jats:italic>O. bifurcum<\/jats:italic> and hookworm prevalences were 53.0% and 86.9%, respectively (<jats:italic>n<\/jats:italic>\u2003=\u20031011). After 12\u2003months, following two rounds of albendazole treatment, prevalences decreased significantly to 5.4% for <jats:italic>O. bifurcum<\/jats:italic> and 36.8% for hookworm (<jats:italic>n<\/jats:italic>\u2003=\u2003535). Twenty\u2010four months after the baseline survey and following a total of four rounds of treatment, prevalences were further reduced to 0.8% and 23.4% for <jats:italic>O. bifurcum<\/jats:italic> and hookworm, respectively (<jats:italic>n<\/jats:italic>\u2003=\u2003478). Overall, there was a significant decrease in the larval counts, measured as geometric mean larval count per 4\u2003g of stool of <jats:italic>O. bifurcum<\/jats:italic> from 3.0 to 0.1 and of hookworm from 47.2 to 1.8. The fourth mass treatment was carried out in April 2003 by the Lymphatic Filariasis Elimination Programme. Overall, compliance to treatment varied from 70% to 80%. In the control area, <jats:italic>Oesophagostomum<\/jats:italic> prevalence increased from 18.5% to 37.0% and the intensity from 0.4 to 1.4. For hookworm, both prevalence (86.1\u201391.3%) and intensity (54.8\u201374.3) increased but not to a significant level. The prospects of eliminating human oesophagostomiasis from the intervention area, while simultaneously achieving an important reduction of hookworm prevalences by albendazole mass treatment, are discussed.<\/jats:p>","DOI":"10.1111\/j.1365-3156.2006.01729.x","type":"journal-article","created":{"date-parts":[[2006,10,20]],"date-time":"2006-10-20T13:21:59Z","timestamp":1161350519000},"page":"1764-1772","source":"Crossref","is-referenced-by-count":23,"title":["Impact of repeated mass treatment on human <i>Oesophagostomum<\/i> and hookworm infections in northern Ghana"],"prefix":"10.1111","volume":"11","author":[{"given":"Juventus B.","family":"Ziem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Magnussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Horton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Von L. L.","family":"Asigri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton M.","family":"Polderman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,10,20]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"133","article-title":"Oesophagostomiasis in man","volume":"31","author":"Barrowclough H","year":"1978","journal-title":"Tropical and Geographical Medicine"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00012840"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(73)90075-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.4269\/ajtmh.2004.71.466","article-title":"Community\u2010wide reduction in prevalence and intensity of intestinal helminths as a collateral benefit of lymphatic filariasis elimination programs","volume":"71","author":"De Rochars MB","year":"2004","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"e_1_2_6_6_1","first-page":"223","volume-title":"Helminth Zoonoses","author":"Gigase P","year":"1987"},{"key":"e_1_2_6_7_1","first-page":"49","article-title":"Oesophagostomiasis in man in north Ghana","volume":"16","author":"Haaf E","year":"1964","journal-title":"Tropical and Geographical Medicine"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(93)90437-U"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-4758(99)01486-6"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.61.951"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1991.44.336"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-4758(99)01428-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.73.867.10817053"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2004.02.007"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1179\/000349804225003370"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2004.07.008"},{"key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1111\/j.1365-3156.2006.01730.x","article-title":"Annual Mass treatment with albendazole might eliminate human oesophagostomiasis from endemic focus in northern Ghana","volume":"11","author":"Ziem JB","journal-title":"Tropical Medicine and International Health"}],"container-title":["Tropical Medicine &amp; International Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-3156.2006.01729.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-3156.2006.01729.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T01:14:27Z","timestamp":1696900467000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-3156.2006.01729.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,20]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1111\/j.1365-3156.2006.01729.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-3156.2006.01729.x","archive":["Portico"],"relation":{},"ISSN":["1360-2276","1365-3156"],"issn-type":[{"value":"1360-2276","type":"print"},{"value":"1365-3156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,20]]}}}